Does Increased Fructose Consumption Increase Atherosclerosis Burden in Patients with NSTEMI?

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dc.contributor.authorKüçük, Uğur
dc.contributor.authorTaşdelen, Bihter
dc.contributor.authorPesenli, Kudret
dc.date.accessioned2025-01-27T19:00:38Z
dc.date.available2025-01-27T19:00:38Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground and Aim: The pathophysiological process of coronary artery disease is not completely understood. According to some studies, fructose consumption is associated with coronary artery diameter change and blood flow; however, the relationship between fructose consumption and coronary atherosclerotic burden has not been adequately studied, and the purpose of our study was to investigate this relationship. Materials and Methods: One hundred and fifty patients with non-ST-elevation myocardial infarction (NSTEMI) who underwent coronary angiography were divided into two groups: low (<23) and high (?23) synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) scores. Fructose consumption was calculated for both groups, and the calculated fructose consumption was compared between the groups. Results: Fructose consumption was higher in patients with a high SYNTAX score than in those with a low SYNTAX score (10.75 ± 2.04 and 6.86 ± 1.54, P < 0.001). Receiver operating characteristic curve analysis showed that the cut-off value of fructose consumption was 41.50 (g) for the prediction of high SYNTAX score (area under the curve: 0.891, sensitivity: 94%, specificity: 73%, P < 0.001). Fructose consumption was determined to be a predictor of high SYNTAX score in patients with NSTEMI (odds ratio: 1,239; 95% confidence interval: 1,146-1,339; P < 0.001). Conclusion: Patients with high SYNTAX scores consumed a higher amount of fructose than those with low SYNTAX scores. High intake of fructose may play a role in coronary atherosclerotic burden score in patients with NSTEMI. © 2024 Galenos Publishing House. All rights reserved.
dc.identifier.doi10.4274/ijca.2024.24008
dc.identifier.endpage12
dc.identifier.issn2405-819X
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85196409439
dc.identifier.scopusqualityQ4
dc.identifier.startpage7
dc.identifier.urihttps://doi.org/10.4274/ijca.2024.24008
dc.identifier.urihttps://hdl.handle.net/20.500.12428/13410
dc.identifier.volume10
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherGalenos Publishing House
dc.relation.ispartofInternational Journal of the Cardiovascular Academy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250125
dc.subjectcoronary atherosclerotic burden; fructose; NSTEMI; SYNTAX score
dc.titleDoes Increased Fructose Consumption Increase Atherosclerosis Burden in Patients with NSTEMI?
dc.typeArticle

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