Does Increased Fructose Consumption Increase Atherosclerosis Burden in Patients with NSTEMI?

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dc.authoridKüçük, Uğur / 0000-0003-4669-7387
dc.authoridPesenli, Kudret / 0000-0002-9615-7920
dc.contributor.authorKüçük, Uğur
dc.contributor.authorTaşdelen, Bihter
dc.contributor.authorPesenli, Kudret
dc.date.accessioned2025-01-27T19:00:38Z
dc.date.available2025-01-27T19:00:38Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground and Aim: The pathophysiological process of coronary artery disease is not completely understood. According to some studies, fructose consumption is associated with coronary artery diameter change and blood flow; however, the relationship between fructose consumption and coronary atherosclerotic burden has not been adequately studied, and the purpose of our study was to investigate this relationship. Materials and Methods: One hundred and fifty patients with non-ST-elevation myocardial infarction (NSTEMI) who underwent coronary angiography were divided into two groups: low (<23) and high (≥23) synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) scores. Fructose consumption was calculated for both groups, and the calculated fructose consumption was compared between the groups. Results: Fructose consumption was higher in patients with a high SYNTAX score than in those with a low SYNTAX score (10.75 ± 2.04 and 6.86 ± 1.54, P < 0.001). Receiver operating characteristic curve analysis showed that the cut-off value of fructose consumption was 41.50 (g) for the prediction of high SYNTAX score (area under the curve: 0.891, sensitivity: 94%, specificity: 73%, P < 0.001). Fructose consumption was determined to be a predictor of high SYNTAX score in patients with NSTEMI (odds ratio: 1,239; 95% confidence interval: 1,146-1,339; P < 0.001). Conclusion: Patients with high SYNTAX scores consumed a higher amount of fructose than those with low SYNTAX scores. High intake of fructose may play a role in coronary atherosclerotic burden score in patients with NSTEMI.
dc.identifier.doi10.4274/ijca.2024.24008
dc.identifier.endpage12
dc.identifier.issn2405-819X
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85196409439
dc.identifier.scopusqualityQ4
dc.identifier.startpage7
dc.identifier.urihttps://doi.org/10.4274/ijca.2024.24008
dc.identifier.urihttps://hdl.handle.net/20.500.12428/13410
dc.identifier.volume10
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherCardiovascular Academy Society
dc.relation.ispartofInternational Journal of the Cardiovascular Academy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250125
dc.subjectcoronary atherosclerotic burden
dc.subjectfructose
dc.subjectNSTEMI
dc.subjectSYNTAX score
dc.titleDoes Increased Fructose Consumption Increase Atherosclerosis Burden in Patients with NSTEMI?
dc.typeArticle

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