Ischemia modified albumin levels and its association with clinical follow-up in acute renal failure

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dc.contributor.authorUzun, Mehmet
dc.contributor.authorTopaloğlu, Ömercan
dc.contributor.authorKurtulmuş, Yusuf
dc.contributor.authorTurkon, Hakan
dc.contributor.authorDuman, Can
dc.contributor.authorKarakas, Burak
dc.contributor.authorAkar, Harun
dc.date.accessioned2025-01-27T19:38:29Z
dc.date.available2025-01-27T19:38:29Z
dc.date.issued2017
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim: In cases with acute ischemia, albumin’s binding capacity for transition metals decreases and the resulting albumin is defined as ischemia modified albumin (IMA). In this study, we aimed to investigate the relationship between IMA and clinical follow-up in patients with acute renal failure (ARF).Material and Methods: Levels of IMA were measured in 51(23 male, 28 female) patients with ARF. Venous blood samples were drawn from patients for biochemical tests and put in plain tubes containing the gel.Results: Mean age of male and female patients was 65.39±15.28 and 70.11±15.25, respectively. The IMA levels in 25.5% of the patients were within the normal range (<400 ABSU), while the IMA levels were higher (>400 ABSU) in 75.5% of the patients. The survival rates of patients in IMA <400 ABSU group for 12 and 24 months were 66.7% and for 30 and 32 months it was 33.3%; while the survival rates of patients in IMA ?400 ABSU group for 12 months were 85.8%, for 24 months were 61.3%, and for 30 and 32 months were 30.6%. No significant difference was determined among survival rates of IMA groups (p=0.719).Conclusion: The comparison between the groups having normal or higher IMA values did not show any significant differences in terms of survival. However, in our study the proportion of patients who needed dialysis during treatment were significantly higher in higher IMA group(IMA?400 ABSU). Therefore, we believe that higher IMA levels may indicate a necessity for dialysis in patients with ARF.
dc.identifier.doi10.5455/jtomc.2016.12.135
dc.identifier.endpage315
dc.identifier.issn1300-1744
dc.identifier.issue3
dc.identifier.startpage310
dc.identifier.trdizinid285152
dc.identifier.urihttps://doi.org/10.5455/jtomc.2016.12.135
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/285152
dc.identifier.urihttps://hdl.handle.net/20.500.12428/17218
dc.identifier.volume24
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofİnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectGenel ve Dahili Tıp
dc.subjectÜroloji ve Nefroloji
dc.titleIschemia modified albumin levels and its association with clinical follow-up in acute renal failure
dc.typeArticle

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