Clinical biomarkers to predict preoperative lymph node metastasis in endometrial cancer

Basit Öğe Kaydı
dc.contributor.authorŞahin, H. Öztürk
dc.contributor.authorYılmaz, Alpay
dc.contributor.authorSıddıkoğlu, Duygu
dc.date.accessioned2025-05-29T05:21:51Z
dc.date.available2025-05-29T05:21:51Z
dc.date.issued2021
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground/Aim: Although the evaluation of preoperative lymph node metastasis is very important for the appropriate approach of the surgeon, it cannot be determined precisely. We aimed to investigate preoperative systemic inflammatory markers and the value of CA 125 in the prediction of lymph node metastasis (LNM) in epithelial endometrial carcinoma. Methods: In our retrospective cohort study, 327 patients were pathologically diagnosed with epithelial endometrial carcinoma and underwent surgical staging including lymphadenectomy. We investigated preoperative serum CA 125, neutrophil/lymphocyte (NLR) and thrombocyte/lymphocyte (PLR) values and their relationship with LNM. ROC analysis was performed to these variables for prediction of LNM. Results: There was a significant difference between histological type (P=0.021), myometrial invasion (P
dc.identifier.doi10.28982/josam.882342
dc.identifier.endpage237
dc.identifier.issn2602-2079
dc.identifier.issue3
dc.identifier.startpage234
dc.identifier.urihttps://doi.org/10.28982/josam.882342
dc.identifier.urihttps://hdl.handle.net/20.500.12428/30813
dc.identifier.volume5
dc.language.isoen
dc.publisherSelçuk BAŞAK
dc.relation.ispartofJournal of Surgery and Medicine
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250529
dc.subjectEndometrial cancer
dc.subjectSystemic inflammatory markers
dc.subjectSerum CA 125 level
dc.subjectLymph node metastasis
dc.titleClinical biomarkers to predict preoperative lymph node metastasis in endometrial cancer
dc.typeResearch Article

Dosyalar

Koleksiyon

DergiPark