Retrospective Analysis of demographic and laboratory characteristics of patients with liver cirrhosis: A single center experience

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dc.contributor.authorÇelik, Zübeyir
dc.contributor.authorBaştürk, Gizem
dc.contributor.authorBeyazit, Yavuz
dc.date.accessioned2025-01-27T19:38:30Z
dc.date.available2025-01-27T19:38:30Z
dc.date.issued2023
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractLiver cirrhosis is a progressive, irreversible disease constituted by a decrease in normal hepatocytes, diffuse fibrosis, and regeneration nodules due to liver damage developed by the chronic inflammation process. This study aims to evaluate patients with liver cirrhosis who applied to Çanakkale Onsekiz Mart University (COMU) Hospital and met the criteria in terms of demographic, etiological, and laboratory values. Patient data were recorded from the hospital data recording system that was admitted to COMU hospital between January 1, 2013, and January 01, 2022. A total of 199 patients with liver cirrhosis were included in the study. Of these patients, 38.2% were female, and 61.8% were male. Their mean age was 63.43±10.73 years. When the patients were evaluated with regard to etiological distribution, the top three etiological causes of cirrhosis were cryptogenic, alcohol-induced, and HBV in 27.6%, 27.1%, and 25.1% of patients, respectively. In terms of complications, ascites were detected in 43.2% of the patients, esophageal varices in 56.3%, splenomegaly in 69.3% and hepatic encephalopathy in 7%. Over the years, the number of patients with cirrhosis due to viral hepatitis has decreased due to an increase in viral hepatitis vaccination campaigns and the spread of antiviral treatments. However, due to the rise in chronic alcohol use, alcohol appears more frequently as a significant risk factor for the etiology of liver cirrhosis.
dc.identifier.doi10.5455/medscience.2023.04.050
dc.identifier.endpage489
dc.identifier.issn2147-0634
dc.identifier.issue2
dc.identifier.startpage484
dc.identifier.trdizinid1186324
dc.identifier.urihttps://doi.org/10.5455/medscience.2023.04.050
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1186324
dc.identifier.urihttps://hdl.handle.net/20.500.12428/17233
dc.identifier.volume12
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectPatoloji
dc.titleRetrospective Analysis of demographic and laboratory characteristics of patients with liver cirrhosis: A single center experience
dc.typeArticle

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