Synthesis of Certain New Morpholine Derivatives Bearing a Thiazole Moiety
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Tarih
2019
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Morpholine is a synthetic simple heterocyclic organic compound having characteristic functional groups ofamine and ether. Feasible physicochemical properties (polarity and solubility), low cost and wideavailability make it a suitable candidate for the synthesis of many potent drugs. In our work, we synthesizeda new series of thiazole substituted morpholine derivatives in two steps. In the first step, thiourea wassynthesized in THF at 70-75OC for 24 h and then in the second step the formation of thiazole ring wasensured in EtOH-DMF (5:5 v/v) at 60°C for 24 hours.
Açıklama
Anahtar Kelimeler
Kimya, Organik, Kimya, Tıbbi, Farmakoloji ve Eczacılık
Kaynak
Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
23
Sayı
4