Digoxin Intoxication

Digoxin is a cardiac glycoside used in the treatment of heart failure and arrhythmia. It has a positive effect on ventricular contraction. However, it causes a decrease in heart rate due to its negative effect on the atrioventricular (AV) node. The narrow therapeutic range of blood digoxin levels cause some concerns about the drug. Our aim in this article is to summarize the effects of digoxin on the cardiovascular system and current approaches in case of possible side effects.