What Should be the Antibiotic Preference in the Treatment of Bacterial Conjunctivitis?

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dc.authoridKomur, Baris/0000-0002-9347-0209
dc.contributor.authorEser, Ilker
dc.contributor.authorAlcali, Alper
dc.contributor.authorComez, Arzu Taskuran
dc.contributor.authorKomur, Bans
dc.contributor.authorOzbey, Nilgun
dc.contributor.authorOtkun, Muserref Tatman
dc.date.accessioned2025-01-27T20:31:24Z
dc.date.available2025-01-27T20:31:24Z
dc.date.issued2010
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose: To investigate the pathogens associated with bacterial conjunctivitis and the in vitro antibiotic sensitivities of these bacteria. Material and Method: Forty-seven (27 female, 20 male) patients with a mean age of 43.7 26.4 (range: 1-84) years, who referred to our out-patient clinic with complaints of burning sensation, stringy discharge and hyperemia between December 2008 and March 2010, who were diagnosed with acute bacterial conjunctivitis, and had no history of any systemic or topical antibiotic use were induded in the study. Samples were taken from both eyes using cotton swabs, cultured onto chocolate and blood agar, and prepared for Gram staining. The identification of organisms was performed by Vitek2 compact system (bioMerieux, France). Antibiograms were evaluated according to the Clinical and Laboratory Standards Institute (CLSI) criteria by disc diffusion method. Results: Twenty-nine of 47 (61.7%) samples were culture-positive. The most common isolated bacteria were coagulasenegative staphylococci (16 cases, 55%). For them, the most sensitive antibiotics, given in decreasing order, were as follows: vancomycin (100%, 21/21), netilmicin (95.7%, 22/23), chloramphenicol (92.6%, 25/27) and tobramycin (91.3%, 21/23). Fluoroquinolones were relatively less sensitive: ofloxacin (75%, 21/28), moxifloxadn (75%, 18/24), dprofloxacin (73.1 %, 19/26). Discussion: Netilmidn, chloramphenicol and tobramydn were found to be more sensitive compared to fluoroquinolones in the treatment of bacterial conjunctivitis. Using these antibiotics as an empirical treatment, taking conjunctival culture of particular cases prior to treatment, and antibiotic switching according to antibiogram will be the most reasonable approach in case of no response to treatment.
dc.identifier.doi10.4274/tjo.40.354
dc.identifier.endpage358
dc.identifier.issn1300-0659
dc.identifier.issn2147-2661
dc.identifier.issue6
dc.identifier.startpage354
dc.identifier.urihttps://doi.org/10.4274/tjo.40.354
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23136
dc.identifier.volume40
dc.identifier.wosWOS:000219188400010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isotr
dc.publisherGalenos Publ House
dc.relation.ispartofTurk Oftalmoloji Dergisi-Turkish Journal of Ophthalmology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectChloramphenicol
dc.subjectciprofloxacin
dc.subjectconjunctivitis
dc.subjectfluroquinolone
dc.subjectmoxifloxacin
dc.subjectnetilmicin
dc.subjectofloxacin
dc.subjectstaphylococcus
dc.subjecttobramycin
dc.titleWhat Should be the Antibiotic Preference in the Treatment of Bacterial Conjunctivitis?
dc.typeArticle

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