Cerebrospinal Fluid and Serum Autoantıbodıes in Drug-Resistant Temporal Lobe Epilepsıes: Case Series

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dc.contributor.authorKabay, Sibel Canbaz
dc.contributor.authorTüzün, Erdem
dc.contributor.authorAkdağ, Gönül
dc.contributor.authorÇetiner, Mustafa
dc.contributor.authorAyas, Selahattin
dc.contributor.authorKaraman, Handan Işın Özışık
dc.contributor.authorArıkan, Fatma Akkoyun
dc.date.accessioned2025-01-27T19:22:55Z
dc.date.available2025-01-27T19:22:55Z
dc.date.issued2023
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractWe aimed to investigate the presence of neuronal antibodies in serum and cerebrospinal fluid(CSF) analysis of patients with drug resistant temporal lobe epilepsy. We evaluated 8 patients who accepted lumbar puncture with a diagnosis of drug resistant temporal lobe epilepsy. Neuronal autoantibodies were found to be negative in both serum and CSF in all patients. We investigated neuronal antibodies and clinical features in cases who were followed up for drug-resistant temporal lobe epilepsy and suspected of autoimmune epilepsy. Although neuronal antibodies were not detected in CSF and serum examinations, this may be related to the early age of onset in our study group. Autoimmune epilepsy should be considered among the differantial diagnosis with a subacute clinic, unusually high seizure frequency, variety and variability of seizures, resistance to antiseizure medications(ASMs), presence of an autoimmune disease in the person or his/her family, history of cancer or viral prodroma, demonstration of CNS inflammation and detection of neural antibodies.
dc.identifier.doi10.20515/otd.1167517
dc.identifier.endpage129
dc.identifier.issn1305-4953
dc.identifier.issn2587-1579
dc.identifier.issue1
dc.identifier.startpage125
dc.identifier.trdizinid1197412
dc.identifier.urihttps://doi.org/10.20515/otd.1167517
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1197412
dc.identifier.urihttps://hdl.handle.net/20.500.12428/15289
dc.identifier.volume45
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofOsmangazi Tıp Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectTıbbi Etik
dc.subjectNörolojik Bilimler
dc.subjectPediatri
dc.subjectPsikiyatri
dc.titleCerebrospinal Fluid and Serum Autoantıbodıes in Drug-Resistant Temporal Lobe Epilepsıes: Case Series
dc.typeArticle

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