Circulating Salusin-beta Levels in Various Open-Angle Glaucoma Types
| dc.contributor.author | Turgut, Burak | |
| dc.contributor.author | Mercan, Kadir | |
| dc.contributor.author | Ilhan, Nevin | |
| dc.contributor.author | Demır, Nesrin | |
| dc.contributor.author | Catak, Onur | |
| dc.date.accessioned | 2025-01-27T19:34:54Z | |
| dc.date.available | 2025-01-27T19:34:54Z | |
| dc.date.issued | 2021 | |
| dc.department | Çanakkale Onsekiz Mart Üniversitesi | |
| dc.description.abstract | Purpose: To evaluate the levels of salusin-beta (?-Sal) in the serum in patients with open-angle glaucoma.\rMaterials and Methods: This pilot work was designed as an institutional controlled comparative clinical study. The serum ?-Sal levels of age\rand sex-matched 20 healthy volunteers as controls (Group 1), 15 patients with normal-tension glaucoma (NTG) (Group 2), 18 patients with\rpseudoexfoliative glaucoma (PXG) (Group 3) and 26 patients with primary open-angle glaucoma (POAG) (Group 4) were measured with the\renzyme-linked immunosorbent assay (ELISA) method.\rResults: There was no statistically signifi cant difference concerning age and gender among the groups (p>0. 05). The mean serum ?-Sal levels\rin Group 1, Group 2, Group 3 and Group 4 were 4977.02±3741.44 pg/mL; 1086.57±253.41 pg/mL; 1044.98±268.80 pg/mL and 868.32±181.78\rpg/mL, respectively. Although the mean ?-Sal levels in all glaucoma groups seem numerically lower than the control group, there was no\rstatistically signifi cant difference between the serum ?-Sal concentrations of the study groups (p>0.05).\rConclusion: These fi ndings suggest that serum salusin-? levels are not different among various open-angle glaucoma types. However,\rtheoretically, ?-Sal may contribute to the pathogenesis of glaucoma and may play a neuroprotective hormone in glaucoma. Further studies with\rlarge patient population are required to say whether ?-Sal plays a role in the pathogenesis of glaucomatous optic neuropathy. | |
| dc.identifier.doi | 10.37844/glauc.cat.2021.16.10 | |
| dc.identifier.endpage | 57 | |
| dc.identifier.issn | 1305-9173 | |
| dc.identifier.issn | 2717-7157 | |
| dc.identifier.issue | 1 | |
| dc.identifier.startpage | 53 | |
| dc.identifier.trdizinid | 510951 | |
| dc.identifier.uri | https://doi.org/10.37844/glauc.cat.2021.16.10 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/tr/yayin/detay/510951 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12428/16762 | |
| dc.identifier.volume | 16 | |
| dc.indekslendigikaynak | TR-Dizin | |
| dc.language.iso | en | |
| dc.relation.ispartof | Glokom Katarakt | |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.snmz | KA_TRD_20250125 | |
| dc.subject | Tıbbi Araştırmalar Deneysel | |
| dc.subject | Göz Hastalıkları | |
| dc.title | Circulating Salusin-beta Levels in Various Open-Angle Glaucoma Types | |
| dc.type | Article |
