Antifungal Activity of Seeds of Hyoscyamus niger L. (Henbane) Against Some Clinically Relevant Fungal Pathogens

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dc.authoridDulger, Basaran/0000-0002-3184-2652
dc.authoridGoncu, Beyza/0000-0001-6026-8218
dc.contributor.authorDulger, Basaran
dc.contributor.authorHacioglu, Nurcihan
dc.contributor.authorGoncu, Beyza S.
dc.contributor.authorGucin, Fahrettin
dc.date.accessioned2025-01-27T21:24:00Z
dc.date.available2025-01-27T21:24:00Z
dc.date.issued2010
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe methanolic extracts obtained from the seeds of Hyoscyamus niger L. (Solanaceae) used as traditional medicine in Turkey were investigated for their ability to inhibit clinically relevant fungal pathogens as six Candida species (C. albicans ATCC 10231, C. tropicalis ATCC 13808, C. guilliermondii ATCC 6260, C. krusei ATCC 20298, C. glabrata ATCC 2001 neoformans ATCC 90112 and C. laurentii ATCC 34142) by microbroth dilution method. The plant displayed activity against all fungal cultures tested. The extracts possessed a strong antifungal potency Greater activity was observed against both Cryptococcus species, with MIC values of 15 mu g/mL.
dc.identifier.endpage6324
dc.identifier.issn0970-7077
dc.identifier.issue8
dc.identifier.startpage6321
dc.identifier.urihttps://hdl.handle.net/20.500.12428/29401
dc.identifier.volume22
dc.identifier.wosWOS:000279844900070
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherAsian Journal Of Chemistry
dc.relation.ispartofAsian Journal of Chemistry
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectHyoscyamus niger L.
dc.subjectAntifungal activity
dc.subjectMedicinal plants
dc.titleAntifungal Activity of Seeds of Hyoscyamus niger L. (Henbane) Against Some Clinically Relevant Fungal Pathogens
dc.typeArticle

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