Stria Gravidarum Is Genetic But Not Related With Collagen Gene Polymorphism

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dc.contributor.authorGungor, Cakir A. N.
dc.contributor.authorOguz, S.
dc.contributor.authorUludag, A.
dc.contributor.authorSılan, Fatma
dc.contributor.authorGencer, M.
dc.contributor.authorUysal, A.
dc.contributor.authorIsik, S.
dc.date.accessioned2025-01-27T20:55:53Z
dc.date.available2025-01-27T20:55:53Z
dc.date.issued2013
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBACKGROUND: Striae Gravidarum (SG) is a common problem that complicates the pregnancies. We aimed to evaluate the possible etiologic factors of SG and the possible importance of collagen polymorphism on SG. METHODS: Totally 151 parous women were evaluated for SG and its possible risk factors and their collagen1A1 (coll 1A1) gene polymorphism were investigated. RESULTS: Risk factors that might affect the striae score were evaluated by univariate variant analysis (ANCOVA) and only the maternal striae history seemed to be related with the stria formation. col 1A1 G2046T polymorphism is frequent in the SG group but the difference was not statistically significant (Odds ratio 1.33, % 95CI 0.36-4.86, p= 0.66). CONCLUSION: As the best of our knowledge this is the first study that searches for the relationship between col 1A1 polymorphism and SG. We failed to show a relationship between SG and col 1A1 polymorphism. Gene polymorphisms might be various among the different races and ethnic groups. So studies with either the larger sample size or the other races must be done.
dc.identifier.endpage137
dc.identifier.issn1529-9120
dc.identifier.startpage131
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26225
dc.identifier.volume15
dc.identifier.wosWOS:000334663400001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherGene Therapy Press
dc.relation.ispartofGene Therapy and Molecular Biology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectcollagen
dc.subjectgenetic polymorphism
dc.subjectrisk factors
dc.subjectstretch marks
dc.subjectstria distensae
dc.titleStria Gravidarum Is Genetic But Not Related With Collagen Gene Polymorphism
dc.typeArticle

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