Are patients with lichen planus really prone to urolithiasis? Lichen planus and urolithiasis

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dc.authoridOguz, Isil Deniz/0000-0001-8628-6107
dc.contributor.authorOguz, Ural
dc.contributor.authorTakci, Zennure
dc.contributor.authorOguz, Isil Deniz
dc.contributor.authorResorlu, Berkan
dc.contributor.authorBalta, Ilknur
dc.contributor.authorUnsal, Ali
dc.date.accessioned2025-01-27T21:19:27Z
dc.date.available2025-01-27T21:19:27Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose: to investigate whether patients with lichen planus (LP) are really prone to urolithiasis or not. Patients and Methods: We performed a prospective analysis of 40 patients diagnosed with lichen planus (LP) (group I), and 40 volunteers did not have LP before (group II). Participants were all checked for urolithiasis by radiological investigations. Blood samples were analyzed for biochemistry parameters including calcium and uric acid. 24-h urine samples were analyzed to investigate oxalate, citrate calcium, uric acid, magnesium, sodium and creatinine. Results: Men/women ratio and mean age were similar between group I and II (p> 0.05). A presence or history of urolithiasis was detected in 8 (20%) and 2 (% 5) patients in group I and II, respectively (p< 0.05). Hypocitraturia was the most common anomaly with 35% (n: 14) in group I. The rate of hypocitraturia in group II was 12.5% (n: 5) and the difference was statistically significantly different (p= 0.036). In group I, hyperuricosuria and hyperoxaluria followed with rates of 27.5% (n: 11) and 25% (n: 10), respectively. The rate of hyperuricosuria and hyperoxaluria were both 5% (n: 2) in group II and the differences were significant (p< 0.05). Hyperuricemia was another important finding in the patients with LP. It was detected in 13 (32.5%) patients in group I and in 1 (2.5%) participant in group II (p= 0.001). Conclusion: According to our results, metabolic disorders of urolithiasis were highly detected in the patients with LP. However, similar to the etiology of LP, the exact reasons for these metabolic abnormalities in LP remain a mystery.
dc.identifier.doi10.1590/S1677-5538.IBJU.2015.0364
dc.identifier.endpage577
dc.identifier.issn1677-5538
dc.identifier.issn1677-6119
dc.identifier.issue3
dc.identifier.pmid27286123
dc.identifier.startpage571
dc.identifier.urihttps://doi.org/10.1590/S1677-5538.IBJU.2015.0364
dc.identifier.urihttps://hdl.handle.net/20.500.12428/28616
dc.identifier.volume42
dc.identifier.wosWOS:000380066200025
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBrazilian Soc Urol
dc.relation.ispartofInternational Braz J Urol
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectLichen Planus, Oral
dc.subjectUrolithiasis
dc.subjectSkin Diseases, Papulosquamous
dc.subjectMetabolic Diseases
dc.titleAre patients with lichen planus really prone to urolithiasis? Lichen planus and urolithiasis
dc.typeArticle

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