Contribution of Neutrophil/Lymphocyte Ratio, RDW, RPR, MPV and MPR Indexes to Febrile Seizure Diagnosis

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dc.authoridKasap, Tolga/0000-0002-1046-7638
dc.authoridCokyaman, Turgay/0000-0002-7108-6839
dc.contributor.authorCokyaman, Turgay
dc.contributor.authorKasap, Tolga
dc.date.accessioned2025-01-27T20:20:16Z
dc.date.available2025-01-27T20:20:16Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractINTRODUCTION: In this study, it was aimed to investigate in detail the contribution of hemogram indices such as neutrophil/lymphocyteratio (NLR), red blood cell distribution width (RDW), RPR, MPR, mean platelet volume (MPV), and platelet count (PLT) to the diagnosis of febrile seizure (FS). MATERIALS and METHODS: 91 FS, 116 febrile disease and 100 healthy control cases were included in the study. Significant hemogram indices in favor of FS were determined as a result of double and triple group comparisons with appropriate statistical analyzes, and diagnostic cut-off values, sensitivity and specificity were calculated for FS diagnosis according to receiever operating characteristic (ROC) curve analysis. RESULTS: NLR index was significantly higher in the FS group. The median was 2.6 in the FS group, 1.6 and 0.7 in the febrile disease and healthy control groups, respectively (p<0.001). In the ROC curve analysis, the cut-off values, sensitivity and specificities of the NLR index for FS diagnosis were determined. The 1/ RPR index was found to be statistically significantly lower in FS group. It was found to be 20.5 in the FS group, 23.3 and 23.2 in the febrile disease and healthy control groups, respectively (p=0.003). Similar to the NLR, cut-off values, sensitivity and specificities were calculated for FS diagnosis in the ROC curve analysis within the 1/RPR index. CONCLUSIONS: NLR and 1/RPR indexes are cheap and easily accessible hemogram parameters that can contribute to the diagnosis of FS. They can be used simply by practitioners and pediatricians in emergency rooms and out patient clinics
dc.identifier.endpage357
dc.identifier.issn1304-9054
dc.identifier.issn1308-6308
dc.identifier.issue3
dc.identifier.startpage346
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21647
dc.identifier.volume18
dc.identifier.wosWOS:000610184400006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isotr
dc.publisherBursa Uludag Univ
dc.relation.ispartofGuncel Pediatri-Journal of Current Pediatrics
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectfebrile seizure
dc.subjecthemogram
dc.subjectindex
dc.subjectchildren
dc.titleContribution of Neutrophil/Lymphocyte Ratio, RDW, RPR, MPV and MPR Indexes to Febrile Seizure Diagnosis
dc.typeArticle

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