Predictive value of inflammatory cell ratios in incidental thyroid papillary carcinoma

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dc.contributor.authorEroğlu, Hüseyin Avni
dc.contributor.authorKarayol, Sunay Sibel
dc.contributor.authorGüvendi, Bülent
dc.contributor.authorAdalı, Yasemen
dc.date.accessioned2025-01-27T19:57:44Z
dc.date.available2025-01-27T19:57:44Z
dc.date.issued2019
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIntroduction: Due to the well-known relationship between inflammatory processes and carcinogenesis, the diagnostic and prognostic value of systemic inflammatorymarkers are at the focus of research. This study aimed to investigate the predictive value of inflammatory cell data obtained from complete blood count in incidentallydetected thyroid papillary carcinoma.Methods: A total of 100 cases were included in the study, consisting of histopathologically diagnosed multinodular hyperplasia (MNH) (N = 20), lymphocytic thyroiditis(LT) (n = 20), incidental thyroid papillary carcinoma (ITPC) (n = 20), incidental papillary carcinoma and lymphocytic thyroiditis (ITPCLT) (n = 20), and thyroid papillarycarcinoma (TPC) (n = 20). Neutrophil / lymphocyte ratio (NLR), platelet/ lymphocyte ratio (PLR), platelet/neutrophil ratio (PNR), lymphocyte/ monocyte ratio (LMR)and lymphocyte/ eosinophil ratio (LER) values were compared between the groups.Results: No significant difference was detected between the groups concerning the mean inflammatory cell and platelet values. However, statistical significance wasobserved between the ITPC and ITPCLT groups regarding the mean LMR and LER values (p=0.009 and p=0.037, respectively). Higher LMR was found in the ITPCgroup, while higher LER was seen in the ITPCLT group.Conclusions: We suggest that besides ratios such as NLR and PLR used as systemic inflammatory markers in carcinogenetic processes, the evaluation of LER and LMRmight be imperative as well. Therefore, these potential markers should be studied in bigger series of tumors, especially where inflammatory processes are involved in theetiology
dc.identifier.endpage88
dc.identifier.issn2458-8865
dc.identifier.issn2459-1505
dc.identifier.issue3
dc.identifier.startpage85
dc.identifier.trdizinid372049
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/372049
dc.identifier.urihttps://hdl.handle.net/20.500.12428/19706
dc.identifier.volume4
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofAile Hekimliği ve Palyatif Bakım
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectGenel ve Dahili Tıp
dc.subjectPatoloji
dc.subjectOnkoloji
dc.titlePredictive value of inflammatory cell ratios in incidental thyroid papillary carcinoma
dc.typeArticle

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