Diagnostic utility of simple hematologic markers in acute gastroenteritis patients admitted to the emergency department

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dc.contributor.authorBardakçı, Okan
dc.contributor.authorDaş, Murat
dc.contributor.authorAkdur, Gökhan
dc.contributor.authorBeyazit, Yavuz
dc.date.accessioned2025-01-27T19:38:30Z
dc.date.available2025-01-27T19:38:30Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe contributions of hematologic parameters to the inflammatory response via different leukocyte and platelet pathways are well known. However, the diagnostic yield ofthese parameters in acute gastroenteritis (AGE) is not yet well understood. This study was planned to investigate the diagnostic value of simple hematological markers,including mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), red cell distribution width (RDW), platelet distribution width (PDW), and platelet-to-lymphocyteratio (PLR), in patients with AGE admitted to the emergency department. A total of 57 patients with AGE of either viral or bacterial origin and 69 age and sexmatchedcontrol subjects were studied. NLR, PLR, MPV, PDW, and RDW values in all patients were calculated and recorded from complete blood cell counts. A total of126 patients (57 men [45.2%] and 69 women [54.8%]) were included in the study. The mean NLR and PLR values of AGE patients were significantly higher than thoseof health controls (NLR = 4.44 ± 4.1 for AGE patients and 2.22 ± 1.2 for controls [P < 0.001]; PLR = 160.4 ± 102.4 for AGE patients and 113.8 ± 42.6 for controls [P =0.02]. ROC curve analysis suggested that the optimum NLR cut-off point for AGE was 2.08, with a sensitivity, specificity, PPV, and NPV of 70%, 65%, 62%, and 72%,respectively (AUC = 0.704). The optimum PLR cut-off point for AGE was 105.55, with sensitivity, specificity, PPV, and NPV of 71%, 50%, 54%, and 68%, respectively(AUC = 0.648). We demonstrated that NLR and PLR levels are elevated in AGE patients. Thus, NLR and PLR levels can be considered a valuable tool to differentiateacute gastroenteritis from other non-inflammatory emergent conditions.
dc.identifier.doi10.5455/medscience.2019.08.9213
dc.identifier.endpage380
dc.identifier.issn2147-0634
dc.identifier.issue2
dc.identifier.startpage376
dc.identifier.trdizinid370440
dc.identifier.urihttps://doi.org/10.5455/medscience.2019.08.9213
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/370440
dc.identifier.urihttps://hdl.handle.net/20.500.12428/17225
dc.identifier.volume9
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofMedicine Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectGenel ve Dahili Tıp
dc.subjectGastroenteroloji ve Hepatoloji
dc.subjectTıbbi Laboratuar Teknolojisi
dc.titleDiagnostic utility of simple hematologic markers in acute gastroenteritis patients admitted to the emergency department
dc.typeArticle

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