The effect of Lymphocyte Monocyte Ratio (LMR) on 30-day mortality of non-HCC post-transplant liver patients admitted to the intensive care unit

Basit Öğe Kaydı
dc.contributor.authorBayrak, Vecihe
dc.contributor.authorGürkök, Mehmet Çağatay
dc.contributor.authorAğalar, Cihan
dc.contributor.authorUnek, Tarkan
dc.contributor.authorAydemir, Ferhan Demirer
dc.contributor.authorVeziroğlu, İrem Erdoğan
dc.contributor.authorGökmen, Necati
dc.date.accessioned2025-05-29T05:37:30Z
dc.date.available2025-05-29T05:37:30Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim: Our study aims to investigate the effect of the LMR value on the 30-day mortality and intensive care hospitalization days of post-transplant liver patients without hepatocellular cancer(HCC) admitted to the intensive care unit(ICU). Methods: Our retrospective study included post-liver transplant patients in the ICU of Dokuz Eylul University Hospital between 2010 and 2020. We recorded patients' age, gender, aetiology of liver disease, donor type (living or deceased), duration of cold ischemia, scores, hospitalization days in the ICU, and 30-day mortality. LMR was calculated by dividing the patient's lymphocyte count by the monocyte count. Statistical analyses were performed using SPSS software version 24.0. Results: 128 (92 male, 36 female) patients were included in our study. Twenty-four patients died within 30 days. The mean LMR was 1.498±2.134, and no significant difference existed between those with and without 30-day mortality (p=0.995). LMR value was not a predictor of mortality and ICU hospitalization days in these patients. Conclusion: Our study revealed that LMR does not predict mortality or hospitalization days in post-liver transplant patients without HCC. The results of our study and previous studies suggest that LMR alteration is associated with an immune state produced by the tumour microenvironment. Our findings suggest that LMR may not be a valuable biomarker for predicting patient outcomes in post-liver transplant patients without HCC. However, this study provides a starting point for further investigation into the role of LMR in cancer diseases.
dc.identifier.doi10.5798/dicletip.1657071
dc.identifier.issn1300-2945
dc.identifier.issn1308-9889
dc.identifier.issue1
dc.identifier.startpage6-Jan
dc.identifier.urihttps://doi.org/10.5798/dicletip.1657071
dc.identifier.urihttps://hdl.handle.net/20.500.12428/31770
dc.identifier.volume52
dc.language.isoen
dc.publisherDicle University
dc.relation.ispartofDicle Tıp Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250529
dc.subjectCritical Care Medicine
dc.subjectHematological changes
dc.subjectLiver failure
dc.subjectViral hepatitis
dc.titleThe effect of Lymphocyte Monocyte Ratio (LMR) on 30-day mortality of non-HCC post-transplant liver patients admitted to the intensive care unit
dc.typeResearch Article

Dosyalar

Koleksiyon

DergiPark