The Relationship between Cardiac Fatty Acid Binding Protein and Acute Coronary Syndrome Risk Scores

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dc.contributor.authorKüçük, Uğur
dc.contributor.authorTürkön, Hakan
dc.contributor.authorAltun, Burak
dc.date.accessioned2025-01-27T19:26:56Z
dc.date.available2025-01-27T19:26:56Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Heart type fatty acid binding protein (H-FABP) is a low moleculer weight major cytoplasmic protein and released quickly from cardiomyocytes in response to myocardial injury. We searched functionality of H-FABP in diagnosis of acute coronary syndrome (ACS) and prevalence of coronary artery disease, relationship with its severity and early diagnosis.Materials and Methods: This was a prospective observational study. We took in 110 patients- aged 18 and above-diagnosed ACS between the dates February 2016 and January 2017. The patient population was divided into two groups as ST segment elevation ACS (STEMI, 52 patients) and Non-ST segment elevation ACS (NSTE-ACS, 58 patients). For H-FABP and cardiac troponin I (cTnI) blood samples of the patients were taken both when they first applied to the hospital and six hours later. Coronary angiography was performed to all the patients. Results: On admission, it wasn’t found a statistically significant relationship in both groups, GRACE (Global Registry of Acute Coronary Events), SYNTAX (The synergy between percutaneous coronary intervention with taxus and cardiac surgery) and between Gensini Risk skores (p=0.056, p=0.791, p=0.278). The H-FABP level of blood samples looked over six hours later with GRACE and Gensini risk scores were statistically significant in the H-FABP positive group (p=0.003, p=0.011). However SYNTAX risk score in H-FABP positive group was not statistically significant (p=0.984).Conclusion: In our study, we demonstrated the relationship between H-FABP and coronary artery disease risk scores and that H-FABP can be used in the diagnosis of ACS.
dc.identifier.doi10.26453/otjhs.566720
dc.identifier.endpage175
dc.identifier.issn2459-1467
dc.identifier.issue1
dc.identifier.startpage165
dc.identifier.trdizinid431598
dc.identifier.urihttps://doi.org/10.26453/otjhs.566720
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/431598
dc.identifier.urihttps://hdl.handle.net/20.500.12428/15673
dc.identifier.volume5
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofOnline Türk Sağlık Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectGenel ve Dahili Tıp
dc.subjectKalp ve Kalp Damar Sistemi
dc.titleThe Relationship between Cardiac Fatty Acid Binding Protein and Acute Coronary Syndrome Risk Scores
dc.typeArticle

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