Experimental intravaginal and intrauterine endometritis model: which model is more useful?

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dc.contributor.authorMakav, Mustafa
dc.contributor.authorKuru, Mushap
dc.contributor.authorBeşeren, Hatice
dc.contributor.authorAdalı, Yasemen
dc.contributor.authorCoşkun, Mustafa Reha
dc.contributor.authorEroğlu, Hüseyin Avni
dc.date.accessioned2025-01-27T19:32:34Z
dc.date.available2025-01-27T19:32:34Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThis study aims to compare the newly created intravaginal endometritis model (IVM) with the intrauterine endometritis model (IUM). E. coli infusion was used as intravaginally for IVM and intrauterinally for IUM model. The animals were exeuted on the 7th day. Histopathological and biochemical analyses [malondialdehyde (MDA), glutathione (GSH), Endocan, Endoglin] were performed. A significant inflammation was determined in IVM and IUM compared to the control. A significant decrease in GSH and a significant increase in MDA and Endoglin were determined in IVM and IUM compared to the control. There was a statistically significant increase in the IUM and a numerical increase in the IVM compared to the control. Endometritis was determined by histopathological and biochemical analyses in both IUM and IVM model. It is suggested that intravaginal administration, which is easier to perform, can be used in experimental endometritis model studies.
dc.identifier.doi10.31797/vetbio.1147776
dc.identifier.endpage375
dc.identifier.issn2548-1150
dc.identifier.issue3
dc.identifier.startpage366
dc.identifier.trdizinid1194658
dc.identifier.urihttps://doi.org/10.31797/vetbio.1147776
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1194658
dc.identifier.urihttps://hdl.handle.net/20.500.12428/16366
dc.identifier.volume7
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofJournal of advances in vetbio science and techniques
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectKadın Hastalıkları ve Doğum
dc.subjectPatoloji
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.subjectVeterinerlik
dc.titleExperimental intravaginal and intrauterine endometritis model: which model is more useful?
dc.typeArticle

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