Antimicrobial activity of the leaves of Verbascum sinuatum L. on microorganisms isolated from urinary tract infection

dc.authoridDulger, Basaran/0000-0002-3184-2652
dc.contributor.authorSener, Alper
dc.contributor.authorDulger, Basaran
dc.date.accessioned2025-01-27T20:29:00Z
dc.date.available2025-01-27T20:29:00Z
dc.date.issued2009
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe ethanolic extracts obtained from the leaves of Verbascum sinuatum L. (Scrophulariaceae) were investigated for their antimicrobial activities against the pathogens causing complicated urine tract infection (Enterococcus faecalis, Escherichia coli, Klebsiella pnemonlae, Pseudomonas aeruginosa, Proteus mirabilis and Candida albicans) disk diffusion method and microdilution method. Some antibacterial and antifungal antibiotics were used as a positive reference standard to determine the sensitivity of the strains. The extracts showed strong antimicrobial activity against Enterococcus faecalis, Proteus mirabilis and Candida albicans with inhibition zones of 20.0, 18.0 and 20.0 mm, with MIC's and MBC's of 4.0 (8.0), 8.0 (16.0) and 8.0 (16.0) mu g/mL, respectively. Also, the extracts exhibited moderate activity against the other test microorganisms. The results demonstrate that the ethanol extract of the aerial parts of Verbascum sinuatum L. has significant activity and suggest that it may be useful in the treatment of infections.
dc.identifier.endpage781
dc.identifier.issn1996-0808
dc.identifier.issue11
dc.identifier.startpage778
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22767
dc.identifier.volume3
dc.identifier.wosWOS:000272702400019
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherAcademic Journals
dc.relation.ispartofAfrican Journal of Microbiology Research
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectUrinary tract infection (UTI)
dc.subjectantimicrobial activity
dc.subjectVerbascum sinuatum
dc.titleAntimicrobial activity of the leaves of Verbascum sinuatum L. on microorganisms isolated from urinary tract infection
dc.typeArticle

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