Changes in liver and kidney antioxidant enzyme activities in the rainbow trout (Oncorhynchusmykiss) exposed cadmium

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dc.contributor.authorHisar, Olcay
dc.contributor.authorYildirim, Sükrü
dc.contributor.authorSönmez, Adem Yavuz
dc.contributor.authorAras, Hatice Nur
dc.contributor.authorGultepe, Nejdet
dc.date.accessioned2025-01-27T19:04:14Z
dc.date.available2025-01-27T19:04:14Z
dc.date.issued2009
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIn vivo effects of cadmium on antioxidant enzymes such as super- oxide dismutase (SOD), catalase (CAT), glutathione Peroxidase (GPx) and glutathione reductase (GSR) investigated in liver and kidney tissues of rainbow trout (Oncorhynchus mykiss). Three test groups of fish were subjected to cadmium in concentrations of 0 (control), 1 and 5 ppm. The duration of exposure was 1,3,5 and 7 d. The antioxidant enzyme activities, measured liver and kidney homogenates, were stimulated by both concentration (1 and 5 ppm) of cadmium chloride. Moreover, the dose-response patterns of the antioxidant enzyme activities in the liver and kidney tissue were very similar. All antioxidant enzyme activities were significantly stimulated on the first day of experiment (Day 1) in the tissues at the both dose of Cd (p < 0.05) while CAT activity was stimulated after 3 days in the tissues at a dose of 1 ppm Cd (p < 0.05). The stimulation effect of Cd on SOD, GPx and GSR activities in the tissues diminished after 7 d cadmium administration. However, this effect of Cd on CAT activity diminished after 5 d. These findings indicate that the tissue antioxidant enzymes function to protect against cadmium toxicity.
dc.identifier.endpage3137
dc.identifier.issn0970-7077
dc.identifier.issue4
dc.identifier.scopus2-s2.0-63849324318
dc.identifier.scopusqualityQ4
dc.identifier.startpage3133
dc.identifier.urihttps://hdl.handle.net/20.500.12428/13875
dc.identifier.volume21
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherChemical Publishing Co.
dc.relation.ispartofAsian Journal of Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subjectAntioxidant enzymes; Cadmium; Rainbow trout
dc.titleChanges in liver and kidney antioxidant enzyme activities in the rainbow trout (Oncorhynchusmykiss) exposed cadmium
dc.typeArticle

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