Electrochemical Investigation of Isoniazid on Poly (p-Aminobenzene Sulfonic Acid) Film Modified Glassy Carbon Electrode
| dc.contributor.author | Demirbilek, Esra | |
| dc.contributor.author | Saglikoglu, Gulsen | |
| dc.contributor.author | Yilmaz, Selehattin | |
| dc.date.accessioned | 2025-01-27T21:01:37Z | |
| dc.date.available | 2025-01-27T21:01:37Z | |
| dc.date.issued | 2015 | |
| dc.department | Çanakkale Onsekiz Mart Üniversitesi | |
| dc.description.abstract | Isoniazid is a tuberculostatic agent effective active compound. A glassy carbon electrode (GCE) was modified with an electropolymerized film of p-aminobenzene sulfonic acid (p-ABSA) in phosphate buffer solution (PBS). The electrochemical properties of isoniazid on modified electrode were studied by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. The polymer film-modified electrode was used to electrochemically detect isoniazid. The polymer film had excellent electrocatalytic activity for the oxidation of isoniazid. A linear calibration curve for DPV analysis was constructed in the isoniazid concentration range 2x10(-5) - 1x10(-4) mol L-1. Limit of detection (LOD) and limit of quantification (LOQ) were obtained as 3.05x10(-6) and 1.01x10(-5) mol L-1 respectively. Isoniazid was determined in tablet dosage form. The proposed method exhibits good recovery and reproducibility. The mechanisms of electropolymerization were also suggested. | |
| dc.identifier.endpage | 4438 | |
| dc.identifier.issn | 1452-3981 | |
| dc.identifier.issue | 5 | |
| dc.identifier.startpage | 4428 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12428/27121 | |
| dc.identifier.volume | 10 | |
| dc.identifier.wos | WOS:000354782200063 | |
| dc.identifier.wosquality | Q3 | |
| dc.indekslendigikaynak | Web of Science | |
| dc.language.iso | en | |
| dc.publisher | Esg | |
| dc.relation.ispartof | International Journal of Electrochemical Science | |
| dc.relation.publicationcategory | info:eu-repo/semantics/openAccess | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.snmz | KA_WoS_20250125 | |
| dc.subject | p-Aminobenzene sulfonic acid | |
| dc.subject | Modified-glassy carbon electrode | |
| dc.subject | Electropolymerization | |
| dc.subject | Electrocatalytic-oxidation | |
| dc.subject | Determination of isoniazid | |
| dc.title | Electrochemical Investigation of Isoniazid on Poly (p-Aminobenzene Sulfonic Acid) Film Modified Glassy Carbon Electrode | |
| dc.type | Article |
