Exploring the Effects of Lucilia sericata Larvae on Biofilm-forming Bacteria in Wounds

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dc.contributor.authorEğribel, Merve
dc.contributor.authorSirekbasan, Serhat
dc.contributor.authorÇakan, Hüseyin
dc.contributor.authorPolat, Erdal
dc.date.accessioned2025-01-27T19:38:43Z
dc.date.available2025-01-27T19:38:43Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Biofilm-induced chronic wound infections are among the most significant causes of treatment failures. Healing chronic wounds with biofilm is a major issue worldwide due to high costs and adverse effects on patients. In this study, we aimed to investigate the impacts of Lucilia sericata larvae on biofilm-forming bacteria in chronic wounds. Method: We recruited 30 patients applying to Istanbul University-Cerrahpasa, Traditional and Complementary Medicine Research and Application Center, Wound Healing Unit, between December 2019 and March 2021. We obtained swab cultures before and immediately after applying Larval Debridement Therapy (LDT). After identifying isolated bacteria, we examined all agents by susceptibility and biofilm formation. Results: While isolating only a single bacterial genus/species in 19 patients, we could detect more than one bacterial genus/species in 11 of them. Moreover, we observed biofilm formation in bacteria isolated from 21 patients, but it was not the case in bacteria grown in 9 patients. Following LDT, we discovered that the biofilm layer on wounds was removed in a short time (two to three sessions). Conclusion: Although many methods are adopted in healing chronic wounds with biofilm formation, they often remain ineffective. The therapy with L. sericata larvae, a simple and effective method, may promote rapid healing of biofilm- forming wounds.
dc.identifier.doi10.5798/dicletip.1220738
dc.identifier.endpage570
dc.identifier.issn1300-2945
dc.identifier.issn1308-9889
dc.identifier.issue4
dc.identifier.startpage565
dc.identifier.trdizinid1169644
dc.identifier.urihttps://doi.org/10.5798/dicletip.1220738
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1169644
dc.identifier.urihttps://hdl.handle.net/20.500.12428/17344
dc.identifier.volume49
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofDicle Tıp Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectTamamlayıcı ve Entegre Tıp
dc.subjectBiyoteknoloji ve Uygulamalı Mikrobiyoloji
dc.titleExploring the Effects of Lucilia sericata Larvae on Biofilm-forming Bacteria in Wounds
dc.typeArticle

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