Effect of acetyl salicylic acid resistance on saphenous vein graft occlusion in patients with metabolic syndrome who had coronary bypass surgery
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Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pulsus Group Inc.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
PURPOSE: The goal of this study was to investigate the effect of acetyl salicylic acid (ASA) resistance on saphenous vein graft occlusion in saphenous vein graft used patients with metabolic syndrome who had CABG. ASA resistance may be higher in patients with metabolic syndrome and saphenous vein graft occlusion and this may result in adverse coronary events. MATERIAL-METHOD: 41 patients with metabolic syndrome who had previously CABG operation for whom saphenous vein graft was used and who currently used 100-300 mg/day ASA, who had postoperative angina pectoris, whose ischemia was determined by noninvasive tests and to whom coronary angiography were performed, were included in our study. The patients were divided into two groups as patients with saphenous vein graft occlusion (n:18) and the patients without saphenous vein graft occlusion (n:23). FINDINGS: In both groups with similar demographic characteristics while ASA resistance was determined in 10 patients with saphenous vein graft occlusion, 7 patients without saphenous vein graft occlusion had ASA resistance. This statistics showed us that in the patients with metabolic syndrome and who had ASA resistance, saphenous vein graft occlusion developed more. CONCLUSION: Although it is important to check ASA resistance in patients with metabolic syndrome, to whom CABG are intended, it is not checked routinely. In patients with metabolic syndrome who have ASA resistance, if CABG is planned high dose ASA treatment can be applied in early period, additional antithrombocyte treatment may be added or arterial graft may be used.
Açıklama
Anahtar Kelimeler
ASA resistance; Coronary artery disease; Metabolic syndrome; Saphenous vein graft occlusion
Kaynak
Experimental and Clinical Cardiology
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
20
Sayı
1
