Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society

dc.authoridUstun, Nuran/0000-0003-1680-1825
dc.authoridAylanc, Hakan/0000-0002-8907-3809
dc.authoridKaratekin, Guner/0000-0001-7112-0323
dc.authoridMert, Mustafa Kurthan/0000-0002-2789-2710
dc.authoridAYDEMIR, OZGE/0000-0002-4106-0873
dc.authoridsahin, suzan/0000-0002-2599-3075
dc.authoridBAS, AHMET YAGMUR/0000-0002-1329-2167
dc.contributor.authorKoc, Esin
dc.contributor.authorDemirel, Nihal
dc.contributor.authorBas, Ahmet Yagmur
dc.contributor.authorIsik, Dilek Ulubas
dc.contributor.authorHirfanoglu, Ibrahim Murat
dc.contributor.authorTunc, Turan
dc.contributor.authorSari, Fatma Nur
dc.date.accessioned2025-01-27T20:17:01Z
dc.date.available2025-01-27T20:17:01Z
dc.date.issued2019
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey. Material and methods A prospective cohort study was performed between April 1, 2016 and April 30, 2017. The study included VLBW infants admitted to level III NICUs. Perinatal and neonatal data of all infants born with a birth weight of.1500 g were collected for infants who survived. Results Data from 69 NICUs were obtained. The mean birth weight and gestational age were 1137 +/- 245 g and 29 +/- 2.4 weeks, respectively. During the study period, 78% of VLBW infants survived to discharge and 48% of survived infants had no major neonatal morbidity. VLBW infants who survived were evaluated in terms of major morbidities: bronchopulmonary dysplasia was detected in 23.7% of infants, necrotizing enterocolitis in 9.1%, blood culture proven late-onset sepsis (LOS) in 21.1%, blood culture negative LOS in 21.3%, severe intraventricular hemorrhage in 5.4% and severe retinopathy of prematurity in 11.1%. Hemodynamically significant patent ductus arteriosus was diagnosed in 24.8% of infants. Antenatal steroids were administered to 42.9% of mothers. Conclusion The present investigation is the first multicenter study to include epidemiological information on VLBW infants in Turkey. Morbidity rate in VLBW infants is a serious concern and higher than those in developed countries. Implementation of oxygen therapy with appropriate monitoring, better antenatal and neonatal care and control of sepsis may reduce the prevalence of neonatal morbidities. Therefore, monitoring standards of neonatal care and implementing quality improvement projects across the country are essential for improving neonatal outcomes in Turkish NICUs.
dc.description.sponsorshipTurkish Neonatal Society [2-2016]; Turkish Neonatal Society
dc.description.sponsorshipThis study was supported by the Turkish Neonatal Society, http://www.neonatology.org.tr, number 2-2016, received by AYB. Turkish Neonatal Society funded the study's online registry system. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
dc.identifier.doi10.1371/journal.pone.0226679
dc.identifier.issn1932-6203
dc.identifier.issue12
dc.identifier.pmid31851725
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0226679
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21464
dc.identifier.volume14
dc.identifier.wosWOS:000534242500056
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherPublic Library Science
dc.relation.ispartofPlos One
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectBronchopulmonary Dysplasia
dc.subjectNecrotizing Enterocolitis
dc.subjectMorbidity
dc.subjectMortality
dc.subjectHealth
dc.subjectPrematurity
dc.subjectInfections
dc.subjectCountries
dc.subjectDistress
dc.subjectSepsis
dc.titleEarly neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society
dc.typeArticle

Dosyalar