Evaluation of surface ECG changes in pregnant women with gestational diabetes mellitus

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dc.contributor.authorGencer, Meryem
dc.contributor.authorGazi, Emine
dc.contributor.authorTemiz, Ahmet
dc.contributor.authorHacivelio?lu, Servet
dc.contributor.authorGüngör, Ayşe çakir
dc.contributor.authorBarutçu, Ahmet
dc.contributor.authorAltun, Burak
dc.date.accessioned2025-01-27T19:05:52Z
dc.date.available2025-01-27T19:05:52Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Gestational diabetes mellitus (GDM) has an increased risk of maternal and fetal complications. Increased maternal cardiac risk is one of the most important complications. QT dispersion and Tp-e duration are findings of surface electrocardiogram (ECG) and they are used an index of inhomogeneity in ventricular electrical activity, and prolongation of QT dispersion is related to increased incidence of ventricular arrhythmias. In this study, we aimed to investigate QT dispersion, Tp-e interval and Tp-e/QT ratio in pregnant women with GDM and emphasize the increased cardiac risk and the importance of GDM screening Methods: Thirty pregnant women with GDM (mean age 27.3±6.1 years) and 23 normal pregnant women (30.2±5.4 years) were included in the study. A 12-lead surface electrocardiogram was used to evaluate QT and Tp-e durations for all participants. All QT intervals were corrected for heart rate using *1*?ş q L"2K, NBazett's formula. QT dispersion was defined as the difference between the maximum corrected QT and minimum corrected QT duration. Student's t test or Mann-Whitney U was used to compare groups. The results were evaluated at the p<0.05 significance level. Results: Mean age, body mass index, blood pressure, heart rate and gestational week of pregnancy were similar between the two groups. QT dispersion (54±13 msc vs. 44±12 msc, p=0.006), Tp-e (81±7 msc vs. 76±8msc, p=0.013) and corrected Tp-e (102.4±9.7msc vs. 96.5±8.2msc, p=0.038) were significantly longer in pregnant women with GDM. The Tp-e/QT corrected ratio was found to be higher in GDM patients (0.19±0.01 vs. 0.18±0.02, p=0.040). Conclusion: Our results suggest that QT dispersion, Tp-e interval and Tp-e/QTc ratio are increased in pregnant women with GDM compared to non-diabetic pregnant women. For this reason we suggest GDM screening for all healthy pregnant women and evaluation the long-term cardiac risks.
dc.identifier.endpage231
dc.identifier.issn0393-6384
dc.identifier.issue1
dc.identifier.scopus2-s2.0-84896888828
dc.identifier.scopusqualityN/A
dc.identifier.startpage227
dc.identifier.urihttps://hdl.handle.net/20.500.12428/14015
dc.identifier.volume30
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherActa Medica Mediterranea
dc.relation.ispartofActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subjectGestational diabetes mellitus; QT dispersion; Tp-e interval; Tp-e/QT ratio
dc.titleEvaluation of surface ECG changes in pregnant women with gestational diabetes mellitus
dc.typeArticle

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