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    Alkaloids of marine macroalgae
    (Springer Berlin Heidelberg, 2013) Güven, Kasım Cemal; Coban, Burak; Sezik, Ekrem; Erdugan, Hüseyin; Kaleağasioğlu, Ferda
    Marine alkaloids have their origins from marine organisms including marine macroalgae. On the other hand, some marine algal alkaloids such as phenylethylamine derivatives were previously isolated from terrestrial plants. The other groups of alkaloids like indole derivatives and halogenated alkaloids are specific for algae. Most of the indole group alkaloids are concentrated in red algae. Green algae are rich of bromine- and chloride-containing alkaloids. These halogenated alkaloids of algae are not present in terrestrial plants and are specific for algae and sea organisms. Marine algae contain 44 alkaloids, consisting of 1 phenylethylamine, 41 indole, and 1 naphthyridine derivates. In the halogenated alkaloid group, there are 25 bromine-containing compounds, among which 7 have chlorine and 5 have sulfur, additionally. © Springer-Verlag Berlin Heidelberg 2013.
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    Öğe
    HHCP contamination in marine alga laurencia pyramidalis bory de saint-vincent ex Kützing
    (2013) Guven, Kasim Cemal; Coban, Burak; Oz?kirimli, Sumru; Erdugan, Hüseyin; Sezik, Ekrem
    This paper describes isolation and indentification of HHCP (Galaxolide®) as pollutant in red alga Laurencia pyramidalis Bory de Saint-Vincent ex Kützing (Syn. Laurencia obtusa var. pyramidata Bory ex J. Agardh) collected from Igneada (Black Sea coast) by GC/MS analysis. It was previously found as a pollutant in Danube River which consequently contaminates the Black Sea. It was suggested that this is a contamination of alga because it was not found in the same species collected from Assos (Çanakkale). This is the first record of HHCP contamination in algae. © by PSP.
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    Öğe
    HHCP CONTAMINATION IN MARINE ALGA LAURENCIA PYRAMIDALIS BORY DE SAINT-VINCENT EX KUTZING
    (Parlar Scientific Publications (P S P), 2013) Guven, Kasim Cemal; Coban, Burak; Ozkirimli, Sumru; Erdugan, Huseyin; Sezik, Ekrem
    This paper describes isolation and indentification of HHCP (Galaxolide (R)) as pollutant in red alga Laurencia pyramidalis Bory de Saint-Vincent ex Kutzing (Syn. Laurencia obtusa var. pyramidata Bory ex J. Agardh) collected from Igneada (Black Sea coast) by GC/MS analysis. It was previously found as a pollutant in Danube River which consequently contaminates the Black Sea. It was suggested that this is a contamination of alga because it was not found in the same species collected from Assos (Canakkale). This is the first record of HHCP contamination in algae.
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    Öğe
    Pharmacology of macroalgae alkaloids
    (Springer Berlin Heidelberg, 2013) Kaleağasioğlu, Ferda; Güven, Kasim Cemal; Sezik, Ekrem; Erdugan, Hüseyin; Coban, Burak
    Constituents of marine algae gained importance in the last four decades due to the growing interest in their potential for medicinal use. Till today, 44 alkaloids were isolated from macroalgae; some of which were reported to induce important pharmacological effects. These alkaloids can be classified under four groups as 2-phenylethylamine, indole, halogenated indole, and 2,7-naphthyridine derivatives, and each group displays a relatively distinguished activity profile. Overall, pharmacological effect spectrum of macroalga alkaloids is wide and includes neuromodulation, neurotransmission, growth regulation, cytotoxicity, angiogenesis, antioxidation as well as antibacterial, antifungal, and larvicidal activities. © Springer-Verlag Berlin Heidelberg 2013.
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    Öğe
    Volatile oils from marine macroalgae
    (Springer Berlin Heidelberg, 2013) Güven, Kasim Cemal; Sezik, Ekrem; Kaleağasioğlu, Ferda; Erdugan, Hüseyin; Coban, Burak; Karakaş, Elif
    Volatile oils of algae contain a variety of compounds. The main group, terpenes, contains acyclic: linalool, geraniol, citronellol; monocyclic: limonene, 1-8-cineol, p-cymene; bicyclic: ?- and ?-pinene, cadinene, aromatic eugenol, and isoeugenol. The others are benzaldehyde, phenol, p-cresol, various acids, alcohols, aldehydes, amines, ketones, sulfur containing and halogenated compounds. When volatile oil components of algae and terrestrial plants are compared, the algae were found to be relatively poor. Importantly, halogenated compounds occur only in algae, but not in terrestrial plants. In this chapter, we present briefly but comprehensively the occurrence of various volatile compounds in different classes of algae. © Springer-Verlag Berlin Heidelberg 2013.