Yazar "Karatay, Ahmet" seçeneğine göre listele
Listeleniyor 1 - 9 / 9
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Amino-functionalized nitrogen-doped graphene quantum dots and silver-graphene based nanocomposites: Ultrafast charge transfer and a proof-of-concept study for bioimaging applications(Elsevier B.V., 2022) Karatay, Ahmet; Erdener, Diğdem; Gürcan, Cansu; Yıldız, Elif Akhüseyin; Yılmazer, Açelya; Boyacıoğlu, Bahadır; Yıldız, MustafaRecent advances in nanotechnology have led to the use of graphene quantum dots (GQDs) for functional imaging and cancer therapy. Thanks to the physicochemical properties of graphene, GQDs have been functionalized and modified to improve their biological properties. In this study, polyethyleneimine functionalized nitrogen-doped graphene quantum dots (PEI N-doped GQDs) and silver nanoparticles/nitrogen-doped graphene quantum dots (AgNPs/PEI N-doped GQDs) nanocomposites have been developed. The PEI N-doped GQDs show a strong emission spectrum at maximum 446 nm with 356 nm excitation wavelength while AgNPs/PEI N-doped GQDs nanocomposites indicate weak fluorescence intensity at maximum 446 nm with 344 nm excitation wavelength. Based on the femtosecond transient absorption spectroscopy measurements, this emission quenching can be attributed that the excited state lifetime of PEI N-doped GQDs decreasing in the presence of AgNPs due to ultrafast electron transfer from PEI N-doped GQDs to AgNPs. It is also supported by theoretical results sensing ability of AgNPs/PEI N-doped GQDs nanocomposite is better than that of PEI N-doped GQDs. When lung adenocarcinoma cells (A549) were treated with GQDs, material-specific fluorescent signals were obtained from the cytoplasm of cells only treated with Ag/PEI N-doped GQDs, as compared with N-doped GQDs. Overall, this study shows that Ag/PEI N-doped GQDs are promising nanosystems for bioimaging applications.Öğe Chromogenic sensing, biological, and optical properties of Schiff bases of 2-amino-6-methoxybenzothiazole(Elsevier B.V., 2024) Akhüseyin Yıldız, Elif; Pepe, Yasemin; Erdener, Diğdem; Karatay, Ahmet; Boyacıoğlu, Bahadır; Ünver, Hüseyin; Yapar, Gönül; Demir, Neslihan; Yıldız, MustafaIn this study, a new series of Schiff base benzothiazole derivatives were synthesized and their structures were characterized by elemental analysis, FTIR, UV–VIS and NMR spectroscopy. The biological, sensory and photophysical properties of the benzothiazole derivatives were investigated. The sensing properties of the compounds were investigated UV–VIS spectroscopically, calorimetrically and theoretically. All compounds showed colorimetric, fluorometric and spectroscopic sensor properties for F−, CN−, AcO−, H2PO4− and OH− anions. Furthermore, DNA binding, DNA cleavage and antioxidant activities of compounds 1-4 were investigated. All compounds affected pBR322 DNA both hydrolytically and oxidatively, interacted with DNA in electrostatic mode, and also compounds 1 and 2 exhibited antioxidant activity close to standard BHT. In addition, the effects of electron donating and accepting substituents on the emission properties and charge transfer dynamics were investigated by fluorescence and femtosecond transient absorption spectroscopy measurements, respectively. According to fluorescence measurements, compounds 3 and 4 showed emission signal, while compounds 1 and 2 showed fluorescence quenching and weaker emission signal.Öğe Colorimetric chemical sensing properties of 3-amino-4-hydroxybenzene- sulfonic acid-based Schiff bases containing electron donor-acceptor groups(Elsevier, 2023) Yildiz, Elif Akhuseyin; Pepe, Yasemin; Erdener, Digdem; Karatay, Ahmet; Boyacioglu, Bahadir; Unver, Huseyin; Yapar, GonulA new series of aminobenzene sulfonic acid-based Schiff bases (1-3) were synthesized from the reaction of 3-amino-4-hydroxybenzenesulfonic acid with 5-methyl, 5-nitro and 5-bromo-salicylaldehyde. The colorimetric and UV-Vis spectroscopic responses of compounds in DMSO to addition of equivalent number of anions (F-, Br-, I-, CN-, SCN-, ClO4-, HSO4-, AcO-, H2PO4-, N3- and OH-) were investigated. Additionally, biological activities of the compounds; antimicrobial and DNA binding properties, were investigated. A DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) free radical method was used to measure antioxidant activity, and 4-hydroxy-3-(2-hydroxy-5-methylbenzylideneamino)benzene sulfonic acid (1) displayed greater antioxidant activity than butylated hydroxytoluene (BHT). Studied compounds demonstrated emission properties over a wide range of visible spectrum, and compound 4-hydroxy-3-(2-hydroxy-5-nitrobenzylideneamino)benzenesulfonic acid (2) has hyp-sochromic shift by incorporating NO2 in comparison with other compounds. Femtosecond transient absorption spectroscopy measurements showed that compounds 4-hydroxy-3-(2-hydroxy-5-nitrobenzylideneamino)benze-nesulfonic acid (2) and 3-(5-bromo-2-hydroxybenzylideneamino)-4-hydroxybenzenesulfonic acid (3), incorpo-rated nitro and bromine groups and possessing electron accepting features have fast triplet transition. This study provides a novel design strategy for biological activity and colorimetric probing features of aminobenzene sul-fonic acid-based Schiff bases.Öğe Colorimetric probe and optical behaviours of new azomethine derivatives of sulfonamide(Elsevier, 2022) Tekin, Sezen; Karatay, Ahmet; Erdener, Digdem; Yildiz, Elif Akhuseyin; Boyacioglu, Bahadir; Unver, Huseyin; Yıldız, MustafaSyntheses, colorimetric anion probe properties, density functional theory (DFT) studies, and optical properties of the Schiffbases; 4-fluoro-N-(2-hydroxy-5-methylbenzylidene) benzenesulfonamide (1), 4fluoro-N-(2-hydroxy-5-nitrobenzylidene)benzenesulfonamide (2) and 4-fluoro-N-[(2-hydroxynaphthalen1-yl)methylene]benzenesulfonamide (3) were reported. The structure of the compounds was elucidated using MS, FTIR, and UV-visible spectroscopic techniques. Their structures were examined by theoretical calculations using density functional theory (DFT). The colorimetric response of the Schiffbase receptors in DMSO was investigated before and after the addition of an equivalent amount of each anion to evaluate the anion recognition properties. The ultrafast transient absorption spectroscopy measurements were performed to investigate the energy transfer dynamics and decay kinetics of the compounds 1-3. The fluorescence and wavelength-dependent pump-probe measurements of the compounds showed that the excited state lifetime of compound 2 is shorter than compounds 1 and 3. The fluorescence properties of compounds 1-3 were compatible with the pump-probe spectroscopy measurements. The compounds with longer ESA lifetimes showed higher fluorescence. (c) 2021 Published by Elsevier B.V.Öğe Colorimetric probing and fluorescent chemosensor features of functionalized sulphonamide-azomethine derivatives(Elsevier Science Sa, 2022) Yildiz, Elif Akhuseyin; Erdener, Digdem; Tekin, Sezen; Karatay, Ahmet; Boyacioglu, Bahadir; Unver, Huseyin; Yıldız, MustafaIn this work, we have experimentally synthesized bromosulfonamide-based azomethine compounds through the reaction of 4-bromobenzenesulfonamide with 2-hydroxy-5-iodobenzaldehyde, 2-hydroxy-5-nitrobenzaldehyde, and 2-hydroxy-l-naphthaldehyde. We have also characterized the molecular structure of the investigated compounds with MS, H-1 NMR, FTIR and UV-vis spectra. Theoretically, using DFT and TD-DFT methods, we computed frontier molecular orbitals (FMOs) energies and UV-vis spectra as well. We have also obtained the electron localization function (ELF) maps to identify electrophilic substitution sites in the molecules and density of states (DOS) diagrams to show the composition of the fragment orbitals that contribute to the molecular orbitals. We have investigated steady-state absorption, emission features, and excited state dynamics to better understand the photophysical process of bromosulfonamide-based azomethines. It has been demonstrated that by adding a naphthalene unit, the absorption properties of azomethine into two branches. Besides, azomethine, including heavy iodo atoms, presents a slight decrement in the fluorescence intensity. According to thorough calculations of charge transfer dynamics using femtosecond transient absorption spectra, the bromosulfonamidebased azomethines with iodo atoms and incorporating naphthalene units exhibit an intersystem crossing mechanism following photoexcitation. The colorimetric response of the compounds in DMSO to the addition of the equivalent amount of anions (F- , Br- , I-, CN-, SCN-, ClO4-, HSO4-, AcO-, H2PO4- , N-3(-) and OH-) was investigated. In this regard, while the addition of F- ,CN- ,AcO- , H2PO4- and OH(- )anions into the solution containing the compounds resulted in a significant color change, the addition of Br-, I-, SCN-, ClO4- HSO4- and N-3 anions resulted in no color change.Öğe Effect of group electronegativity on spectroscopic, biological, chromogenic sensing and optical properties of 2-formyl-benzene sulfonic acid sodium salt-based Schiff bases(Elsevier B.V., 2023) Akhüseyin Yıldız, Elif; Pepe, Yasemin; Erdener, Diğdem; Karatay, Ahmet; Boyacıoğlu, Bahadır; Ünver, Hüseyin; Yapar, Gönül; Demir, Neslihan; Yıldız, Mustafa; Elmalı, AyhanIn this study, 2-formylbenzenesulfonic acid sodium salt-based Schiff bases were synthesized from the reactions of 2-formylbenzenesulfonic acid sodium salt with 2-amino-4-chlorophenol and 2-amino-4-methylphenol. The structure of the compounds was determined by FTIR, UV–Vis and NMR spectroscopy methods using both experimental and DFT methods. The anion sensor properties of the compounds were investigated both UV–Vis spectroscopically and calorimetrically. In addition, the antimicrobial activities, interactions with DNA, DNA cleavage and antioxidant activities of Schiff bases were investigated. Additionally, the effects of group electronegativity on the spectroscopic, biological, chromogenic sensing and optical properties of chlorine and methyl side groups and sodium 2-sulfobenzalidene-aminophenol-based Schiff bases were investigated.Öğe Exploring Charge Transfer Mechanisms in Schiff Base-Modified N-Doped GQDs: Insights from DFT and Pump-Probe Spectroscopy for Bioimaging Applications(Wiley-V C H Verlag Gmbh, 2024) Hance, Saadet; Erdener, Digdem; Ozturk, Berfin Ilayda; Yildiz, Elif Akhuseyin; Karatay, Ahmet; Boyacioglu, Bahadir; Unver, HuseyinIn recent developments, graphene quantum dots (GQDs) have emerged as valuable tools for imaging and biosensing. Various modifications on the GQDs with any desired functionality and attachment of organic molecules and/or nanostructures allow tuning their photophysical properties as well as charge transfer dynamics for bioimaging applications. This study focuses on synthesizing and characterizing of polyethyleneimine-functionalized nitrogen-doped GQDs (NC1), Schiff base- functionalized nitrogen-doped GQDs (NC2), and silver nanocomposites of these Schiff base-functionalized nitrogen-doped GQDs (NC3). We explore their absorption and emission properties to understand their interactions in the ground state. Furthermore, ultrafast transient absorption spectroscopy measurements reveal that the presence of NC3 shortens the excited state lifetime of NC1 due to charge transfer, resulting in reduced fluorescence intensity. Both experimental and DFT results suggest the potential of NC3 for bioimaging and sensing applications, making them promising candidates for phototheranostic purposes.Öğe Naked-eye colorimetric anion probing and fluorescent switching features of conjugated Schiff Bases derived from 4-(Trifluoromethyl) benzenesulfonamide(Elsevier, 2022) Yildiz, Elif Akhuseyin; Tekin, Sezen; Erdener, Digdem; Karatay, Ahmet; Boyacioglu, Bahadir; Unver, Huseyin; Yıldız, MustafaIn this work, synthesis, spectroscopic, density functional theory (DFT) and photophysical studies of the three conjugated benzenesulfonamide Schiff bases were reported. We also calculated the energies of the frontier molecular orbitals (FMOs) and UV-Vis spectra of Schiff bases theoretically using the DFT and TD-DFT methods. Additionally, photophysical properties were investigated by UV-Vis and fluorescence spectroscopy techniques. The ground state interactions show that the absorption band has been separated into two branches and bathochromatically tuned to the visible region, and fluorescence intensity decreased in the case of the Schiff base incorporated naphthalene unit. Furthermore, the charge transfer dynamics of the compounds were analyzed using femtosecond transient absorption spectroscopy measurements proving the triplet-triplet transitions via intersystem crossing mechanism. Based on the ultrafast pump-probe experimental results, as well as decay kinetics of the compounds, the Schiff base with naphthalene unit, showed a fast transition to the triplet state (1.2 ps) as compared to Schiff bases including methyl (4 ps) and chloro (2.7 ps) units. However, upon the addition of various anions, the molecule structure gains anion sensing and fluorescence switching capabilities under daylight and UV light. The obtained experimental results pointed out that the modification of Schiff base molecules with methyl, chlorine and naphthalene units affected its photophysical properties as well as excited-state dynamics significantly.Öğe UV-Vis spectroscopic and colorimetric anion detection and fluorescence properties of new 3-amino-4-hydroxybenzenesulfonic acid-based Schiff bases depending on the strength and position of the electron donor substitution(Iop Publishing Ltd, 2023) Yildiz, Elif Akhuseyin; Pepe, Yasemin; Erdener, Digdem; Karatay, Ahmet; Boyacioglu, Bahadir; Unver, Hueseyin; Yapar, GonulIn this study, 3-amino-4-hydroxybenzenesulfonic acid-based imine compounds; 3-(2,5-dihydroxybenzylideneamino)-4-hydroxybenzenesulfonic acid (1), 3-(2,4-dihydroxybenzylideneamino)-4-hydroxybenzenesulfonic acid (2) and 4-hydroxy-3-(2-hydroxy-3-methoxybenzylideneamino)-4-hydroxybenzenesulfonic acid (3) was synthesized. The compounds were analyzed using various spectroscopy methods, and the experimental UV-vis data matched the theoretical predictions. The compound 1 displayed lower stability, higher reactivity, and easier photoexcitation due to a smaller HOMO-LUMO energy gap. The investigated compounds 1-3 showed promise as chemosensors for anions, providing visible detection in daylight conditions. The compound 3 exhibited selective fluorescence at specific wavelengths. The compounds 1-3 interacted with DNA through electrostatic interactions. Also, compounds 1-3 showed higher antioxidant activity than BHT. However, fluorescence measurements indicated that the emission signals were strongly influenced by the position and strength of the electron-donating group. Adding a hydroxy or methoxy moiety near the -OH group on the phenyl ring decreased the fluorescence signal due to intersystem crossing and intramolecular charge transfer mechanisms, respectively. These findings were supported by femtosecond transient absorption spectroscopy measurements. The results emphasize the significance of substituents in imines derived from 3-amino-4-hydroxybenzenesulfonic acid in determining their biological activities, as well as their optical and sensor properties.
