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    Öğe
    Does the scientific literature provide sufficient know-how for rabbit experiments?
    (2023) Genç, Çiğdem Çetin
    [Abstract Not Available]
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    Öğe
    The effects of type-I collagen membrane, hydroxyapatite, and platelet-rich plasma on bone regeneration: An experimental study
    (2021) Genç, Çiğdem Çetin; Gulsun, Belgin
    Aim: Various methods have been developed to support bone\rreconstruction, including the use of autogenous, allogenic, and synthetic\rbone graft substitutes, membranes, and concentrated supplements. This\rstudy aims to compare the effects of collagen membrane, hydroxyapatite,\rand platelet-rich plasma on the bone regeneration process in a rat model.\rMethodology: The experiment was conducted with 60 female Wistar\ralbino rats. Subjects were divided randomly into three groups (n: 20). In\rthe first group, the right femurs' defects were left empty (group I), and\rtype-I collagen membrane was applied to the left femurs (group II). TypeI collagen membrane + hydroxyapatite (group III) was applied to the second\rgroup, and type-I collagen membrane + hydroxyapatite + platelet-rich\rplasma (PRP) (group IV) was applied to the third group. Thus, a total of 80\rfemurs were included in the study, and defects were evaluated\rhistologically on the 10th, 21st, 45th, and 90th days (n: 5).\rResults: Groups II and III had better osteogenesis scores than group I,\rwhereas group IV had better results than all other groups.\rConclusion: In the PRP group, the osteogenesis scores were significantly\rbetter than the other groups. However, the healing was almost excellent\rin all three study groups (groups II, III, and IV) at the end of the\rexperiment
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    Öğe
    Wharton Kanalında Ektopik Diş: Sıra Dışı Bir Vaka
    (2021) Güner, Rezzan; Genç, Çiğdem Çetin
    Wharton kanalında ektopik diş gelişimi ve sürmesi nadiren kar şılaşılan bir durumdur. Submandibular bezde ve kanalda tıkanıklıklabirlikte ağrı olması, genellikle siyalolitiyazisin düşünülmesine nedenolur. Radyolojik muayenede radyoopak yabancı cisim tespiti; kireç lenmiş yabancı cisim, submandibular tükürük bezinde diş gibi birdenfazla nedenin göstergesi olabilir. Hastalar, genellikle çiğneme sırasındaağrı, ödem ve süpürasyona bağlı ağızda oluşan kötü tattan rahatsızlıkduyarlar. Bu vakada tanı, klinik ve radyolojik değerlendirmeden sonrahistopatolojik olarak doğrulandı. Bu olgu sunumunun amacı Whartonkanalında ektopik diş tespit edilen hastanın klinik, radyolojik ve histo patolojik bulgularını güncel literatür eşliğinde tartışmaktır.