Yazar "Cakici, Veli" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • [ X ]
    Öğe
    Comprehensive Mapping of Psychosocial Burden in Breast Cancer: A Multicenter Cross-Sectional Study in Türkiye
    (Galenos Publ House, 2025) Gokmen, Ivo; Divriklioglu, Didem; Ozcan, Erkan; Cakici, Veli; Coskun, Alper; Demir, Nazan; Topaloglu, Sernaz
    Aim: This study aimed to investigate the sociodemographic and clinical factors associated with depression and anxiety in women diagnosed with breast cancer and to identify predictors that may contribute to psychological distress.Materials and Methods: This multicenter cross-sectional study included 460 breast cancer patients assessed via structured interviews and medical records. Depression and anxiety symptoms were measured using validated tools (Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7), with scores >= 10 indicating clinical significance. Logistic regression analyses identified independent predictors.Results: Clinically significant depression and anxiety were observed in 24.6% and 27.2% of the participants, respectively. Depression was independently associated with younger age [adjusted odds ratio (AOR): 4.68], being childless (AOR: 2.47), low income (AOR: 3.35), limited healthcare access (AOR: 3.34), and low social support (AOR: 6.38). Clinical predictors included premenopausal status (AOR: 2.86), poor sleep (AOR: 2.18), lymphedema (AOR: 2.55), advanced cancer stage (AOR: 1.65), and active chemotherapy (AOR: 2.61). Anxiety was similarly linked to younger age (AOR: 2.93), poor access to care (AOR: 3.84), low social support (AOR: 4.34), and ongoing treatments including chemotherapy and hormone therapy.Conclusion: Depression and anxiety are prevalent among breast cancer patients and are strongly associated with both sociodemographic disadvantages and clinical disease burden. Routine psychological screening should be integrated into oncology care to support patient well-being and optimize outcomes
  • [ X ]
    Öğe
    Lung Adenocarcinoma and Hyperamylasemia Associated with Paraneoplastic Syndrome: A Case Report
    (Galenos Publ House, 2025) Cakici, Veli; Suleyman, Can; Uygun, Gokhan; Yulek, Ozden
    Paraneoplastic syndromes are systemic manifestations arising from tumor-associated biochemical or immunologic effects, occurring independently of direct tumor invasion. While common paraneoplastic syndromes such as hypercalcemia and hyponatremia are frequently observed in lung cancer, hyperamylasemia is a rare phenomenon, particularly associated with metastatic lung adenocarcinoma. A 67-year-old male presented with complaints of fatigue and shortness of breath. Laboratory investigations revealed elevated serum amylase (1330 U/L). The patient had no abdominal symptoms, and imaging showed no pancreatic pathology. Chest computed tomography identified a spiculated lesion in the left upper lobe of the lung, and biopsy confirmed a diagnosis of lung adenocarcinoma. Additional evaluations found no other cause for the amylase elevation, leading to a diagnosis of paraneoplastic hyperamylasemia. Following chemotherapy with carboplatin and paclitaxel, a significant reduction in serum amylase levels was observed, alongside partial tumor regression. This case highlights hyperamylasemia as a rare paraneoplastic syndrome in lung adenocarcinoma. Unexpected biochemical abnormalities in cancer patients should be evaluated as potential paraneoplastic syndromes associated with malignancy and closely monitored. In this case, the decrease in amylase levels following chemotherapy supports a paraneoplastic etiology.