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    An effective treatment for prevention and impediment of atrial fibrillation after cardiac surgery
    (Pulsus Group Inc., 2014) Yener, Ali Umit; Ozkan, Turgut; Cicek, Mustafa Cuneyt; Cicek, Tugba; Baysal, Erkan; Genc, Bahadir; Dogan, Emre
    Atrial fibrillation is a common rhythm disorders after open heart surgery and associated with increased morbidity and mortality. Advanced age, hypertension, COPD are known to be the causes of postoperative atrial fibrillation. However, reactive oxygen radicals formed after open heart surgery have been shown to be involved in the etiology of AF. Besides its expectorant feature, NAC is a molecule known to be an antioxidant. In this retrospective study, we compared the incidence of postoperative AF and onset time of AF in patients who used preoperatively NAC because of COPD and who did not use NAC. In this study, the incidence of atrial fibrillation was significantly lower in patients using NAC preoperatively. Also onset time of AF was significantly longer in patients who used NAC.
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    Effect of acetyl salicylic acid resistance on saphenous vein graft occlusion in patients with metabolic syndrome who had coronary bypass surgery
    (Pulsus Group Inc., 2014) Baysal, Erkan; Yener, Ali Umit; Ozkan, Turgut; Karan, Adnan; Astan, Ramazan; Keskin, Gokhan; Yener, Ozlem
    PURPOSE: The goal of this study was to investigate the effect of acetyl salicylic acid (ASA) resistance on saphenous vein graft occlusion in saphenous vein graft used patients with metabolic syndrome who had CABG. ASA resistance may be higher in patients with metabolic syndrome and saphenous vein graft occlusion and this may result in adverse coronary events. MATERIAL-METHOD: 41 patients with metabolic syndrome who had previously CABG operation for whom saphenous vein graft was used and who currently used 100-300 mg/day ASA, who had postoperative angina pectoris, whose ischemia was determined by noninvasive tests and to whom coronary angiography were performed, were included in our study. The patients were divided into two groups as patients with saphenous vein graft occlusion (n:18) and the patients without saphenous vein graft occlusion (n:23). FINDINGS: In both groups with similar demographic characteristics while ASA resistance was determined in 10 patients with saphenous vein graft occlusion, 7 patients without saphenous vein graft occlusion had ASA resistance. This statistics showed us that in the patients with metabolic syndrome and who had ASA resistance, saphenous vein graft occlusion developed more. CONCLUSION: Although it is important to check ASA resistance in patients with metabolic syndrome, to whom CABG are intended, it is not checked routinely. In patients with metabolic syndrome who have ASA resistance, if CABG is planned high dose ASA treatment can be applied in early period, additional antithrombocyte treatment may be added or arterial graft may be used.
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    Magnesium; the electrolyte that delays the formation of atrial fibrillation
    (Pulsus Group Inc., 2014) Yener, Ali Umit; Ozkan, Turgut; Cicek, Mustafa Cuneyt; Baysal, Erkan; Dogan, Emre; Cicek, Omer Faruk; Genc, Bahadir
    Atrial fibrillation is one of the most common undesirable situation seen after open-heart surgery because of increasing the length of hospital stay, morbidity and mortality. It is revealed that atrial fibrillation may occur as a result of various electrolyte deficiencies such as magnesium. In this retrospective study, we aimed to compare the rhythm outputs of different cardiopulmonary bypass protocols,magnesium included in study group and without magnesium used patients was inserted in control group. The incidence of atrial fibrillation between 2 groups was not statistically significant. Furthermore magnesium treatment delayed the onset of atrial fibrillation in patients after coronary bypass graft surgery.