Yazar "Aksit, E." seçeneğine göre listele

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    BLOOD PRESSURE VARIABILITY AMONG RHEUMATOID ARTHRITIS PATIENTS
    (Lippincott Williams & Wilkins, 2018) Yildirim, O. Turgay; Gonullu, E.; Aydin, F.; Aydin, A. Huseyinoglu; Dagtekin, E.; Aksit, E.; Hasirci, S. Has
    [Anstract Not Available]
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    How can we increase adherence to medical treatment in heart failure patients? A questionnaire study
    (Wiley, 2024) Kaya, H. Hakki; Sahin, A.; Aksit, E.; Yilmaz, M. B.
    [Anstract Not Available]
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    Interpretation of coronary collateral by myocardial perfusion gated spect
    (Springer, 2019) Ozdemir, S.; Barutcu, A.; Tan, Y. Z.; Aksit, E.; Duygu, A.; Ozturk, F. K.
    [Anstract Not Available]
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    Is elabela/toddler a poor prognostic marker in heart failure patients?
    (Lithographia, 2023) Kucuk, U.; Kirilmaz, B.; Kaya, H.; Aksit, E.; Arslan, K.
    Background: Elabela/toddler (ELA-32) is a recently identified endogenous apelin receptor ligand. ELA levels are known to rise in heart failure (HF) patients. However, the association between elevated ELA levels and prognosis in these patients remains unknown. We aimed to investigate whether ELA plasma levels are correlated with prognosis in heart failure patients with reduced ejection fraction (HFrEF). Methods: This case-control cross-sectional study enrolled 150 patients, including 73 HFrEF patients and 77 age- and gender-matched healthy volunteers. We collected a blood sample at hospital admission to measure ELA-32 levels. The study endpoint was cardiovascular mortality or HF-related hospitalization. We followed up all patients in the study for a mean of 7.48 +/- 2.73 months. Results: In patients with HFrEF, ELA-32 levels were higher than those in controls. The levels of ELA-32 showed a significant increase at advanced New York Heart Association stages. In the receiver operating characteristics curve analysis, a cut-off value of the serum ELA-32 level of 8.25 ng/mL showed a sensitivity of 76 % and specificity of 82 % for predicting the study endpoint [area under the curve: 0.84; 95 % confidence interval (CI): 0.72-0.98; p <0.001]. Cardiovascular mortality (p =0.042) and HF-related hospitalization (p <0.001) were statistically more significant in patients with ELA-32 levels greater than 8.25. Age [Hazard ratio (HR) =1.023; 95 % CI: 0.964-1.230, p =0.039], N-terminal =1.142; 95 % CI 1.022-1.547, p =0.028), and ELA-32 >= 8.25 (HR =2.556; 95 % CI: 1.078-3.941, p <0.001) remained independently associated with the risk of study endpoint. Conclusion: For the first time, HF-related hospitalizations and cardiovascular mortality are independently associated with increased ELA-32 levels in patients with HFrEF. HIPPOKRATIA 2023, 27 (4):126-131.
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    NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO ARE INDEPENDENT PREDICTORS FOR BLOOD PRESSURE VARIABILITY
    (Lippincott Williams & Wilkins, 2018) Yildirim, O. Turgay; Aydin, F.; Aydin, A. Huseyinoglu; Dagtekin, E.; Aksit, E.; Hasirci, S. Has
    [Anstract Not Available]
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    Nocturnal blood pressure dipping is similar in rheumatoid arthritis patients as compared to anormal population
    (Springer Heidelberg, 2019) Yildirim, O. Turgay; Gonullu, E.; Aydin, F.; Aksit, E.; Aydin, A. Huseyinoglu; Dagtekin, E.
    ObjectiveRheumatoid arthritis (RA) is asystemic autoimmune inflammatory disorder which further doubles the risk of developing cardiovascular disease. Some studies suggest that in RA patients, the prevalence of hypertension increases due to prednisolone use, clinical status, genetic factors, and physical inactivity. On the other hand, dipper and non-dipper status in RA patients compared to non-RA subjects has not been investigated to our knowledge. Purpose of the study is to investigate whether non-dipper status is more deteriorated in RA patients.MethodsSixty-five RA patients and 61age-sex-matched control patients were evaluated in this cross-sectional study. Patients were classified according to 24-h ambulatory blood pressure monitoring results. Patients with previous hypertension diagnosis, coronary artery disease, and abnormal kidney function were excluded.ResultsMean age of the study sample was 53.712.3years and 40.5% were male. There was no significant difference between groups in terms of basic demographic characteristics. Leukocyte counts (p=0.001), neutrophil counts (p=0.001), and red cell distribution width (p=0.000) were significantly higher in the RA group. ABPM results indicate no significant difference between RA patients and the control group in terms of daytime systolic and diastolic blood pressure, nighttime systolic and diastolic blood pressure, and average systolic and diastolic blood pressure results (p>0.05). There was no statistical difference regarding the non-dipper status of patient groups (p=0.412). Nocturnal blood pressure dipping was significantly similar between groups (p=0.980).ConclusionIn conclusion, RA patients have similar values in terms of nocturnal blood pressure dipping and hypertension diagnosis as compared to normal population.