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Öğe Gastric acid challenge: Mechanical proficiency and surface gloss of tooth-colored restorative materials(Bmc, 2025) Yenidünya, Özge Gizem; Misilli, Tuğba; Yılmaz, EbruBackgroundTo evaluate surface microhardness, roughness, and gloss changes of tooth-colored restorative materials [a direct composite (G-aenial A'Chord), an indirect composite (Gradia Plus), an ormocer (Admira Fusion), a giomer (Beautifil II), and an alkasite (Cention N)] after exposure to simulated gastric acid.MethodsA total of 110 disc-shaped specimens (22 discs of each material) were prepared using silicone molds (8 mmx2 mm) and exposed to either gastric acid or artificial saliva (control). Surface roughness (Ra), gloss (GU), and microhardness (VHN) were measured at baseline and after 96-hour of immersion in the solutions and the respective changes (triangle Ra, triangle GU, triangle VHN) were calculated. Intergroup comparisons were performed using ANOVA (Tukey post hoc) or Kruskal-Wallis tests (Bonferroni correction). Independent samples t-test or Mann-Whitney U test was used for comparisons of each material across immersion media, while paired t-test was applied for time-dependent analyses.ResultsIn the gastric acid medium, changes in all parameters led to significant differences among restorative materials, while in the artificial saliva medium, significant differences were observed in triangle VHN and triangle GU. The statistically significant difference between immersion media was observed in both triangle VHN and triangle Ra values for the giomer group, and in only triangle VHN values for the alkasite and indirect composite groups. In the gastric acid medium, the decrease in VHN and GU values was significant across all subgroups, while the increase in Ra was statistically significant only in the giomer and alkasite groups.ConclusionsWhile the giomer group exhibited the most significant changes in roughness and microhardness following exposure to gastric acid, all tested materials executed clinically admissible results regarding surface gloss.Clinical trial numberNot applicable.Öğe Effects of Detox Juices on Color Stability and Surface Roughness of Universal Chromatic Resin Composites(Operative Dentistry Inc, 2025) Yenidünya, O. G.; Misilli, TuğbaThis study investigated the color stability and surface roughness of universal chromatic resin-based composites (RBCs) after immersion in detox juices. One hundred seventy-six disc-shaped specimens (8 mm in diameter and 2 mm in thickness) were prepared using four universal chromatic RBCs: NeoSpectra ST (NS), Omnichroma (OM), Charisma Topaz One (CO), and G-ae nial Universal Injectable (GI). Specimens of each material were randomly divided into four subgroups (n=11) and immersed in either the assigned detox juices (red, green, or yellow) or distilled water (control). Color and surface roughness measurements were taken at baseline, 15 and 30 days of immersion. Scanning electron microscopy (SEM) was used to evaluate the surface topography of the composites. The color change [CIEDE2000 (Delta E00)] and surface roughness (Ra) values were analyzed using generalized linear models and multiple comparison tests with Bonferroni correction. Correlation analysis was performed using Spearman rank correlation test. The main variable effects of composite and immersion media were significant for both color change and surface roughness parameters (p<0.001). Additionally, the main effect of the evaluation period was significant only for surface roughness (p=0.001). The highest discoloration occurred in the GI group immersed in a red beverage, while the CO group immersed in yellow beverage had the highest Ra values. In SEM analysis, OM demonstrated a more homogeneous filler structure with clearly visible nano-spherical fillers and nanoclusters, contributing to its superior smoothness. Conversely, a significant increase in rough areas was observed, especially in NS exposed to the green beverage and CO exposed to the yellow beverage, after 30 days. While the immersion of resin composites in detox juices induced an acceptable color alteration except for OM and GI groups immersed in the red beverage, all tested materials exhibited clinically admissible results regarding surface roughness.Öğe Home-use agents in the treatment of dentin hypersensitivity: clinical effectiveness evaluation with different measurement methods(Springer Heidelberg, 2025) Ayan, Gizem; Misilli, Tuğba; Buldur, MehmetObjectives This study aimed to evaluate the effectiveness of home-use desensitizing agents over an 8-week period by comparing them using different measurement methods. Methods A randomized, controlled clinical trial was conducted with 180 individuals aged between 18 and 70 who clinically diagnosed dentin hypersensitivity (DH) in two or more non-adjacent teeth. Subjects who met the inclusion criteria (n = 164) were randomly allocated into five test groups-using Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), Arginine, Novamin, Propolis, and Potassium nitrate-and a control group using standard fluoride toothpaste. The status of DH was assessed at week 4 and week 8 by the same independent examiner. Changes from baseline in Dentine Hypersensitivity Experience Questionnaire-15 (DHEQ-15), Schiff Sensitivity Scale (SSS) and Visual Analog Scale (VAS) were analysed using ANOVA and Kruskall-Wallis tests. Results All test groups showed statistically significant improvements in DH at weeks 4 and 8 compared to baseline in the DHEQ-15, VAS, and SSS assessments (p < 0.005). In the control group, significant improvements were observed only in the VAS and SSS measurements from baseline to weeks 8 (p < 0.005). The CPP-ACP group demonstrated the greatest reduction in scores by the end of week 8 compared to baseline, with DHEQ-15 (56.68 +/- 17.87), VAS (6.52 +/- 1.48), and SSS (2.32 +/- 0.56). Conclusions Among the tested agents, the CPP-ACP group demonstrated the most notable reduction in DH symptoms by week 8, highlighting its potential as an effective method for alleviating DH symptoms in a home-use agents. Clinical relevance Home-use desensitizing agents are effective in the treatment of DH, improving the daily activities of patients who cannot access clinical care and ensuring the relief of DH before clinical invasive procedures. Trial registrationClinicalTrials.gov Identifier: NCT06216262.Öğe Evaluation of Plaque Index, Gingival Index and Oral Health-Related Quality of Life in Obese Patients(Universidad de Costa Rica, 2023) Ayan, Gizem; Dayı, BurakObesity is a chronic disease that may be related to caries, periodontitis, xerostomia, and dental erosion, as well as increasing morbidity and mortality. The aim of this study was to evaluate the plaque index (Silness & Löe, 1964), the gingival index (Löe & Silness, 1963), and the oral health-related quality of life (OHRQoL) in obese patients. The study included 45 extremely obese, 45 obese, and 45 normal-weight individuals between the ages of 18 and 58. The plaque index and gingival index of the individuals were determined by clinical examination by probing. In addition, the Oral Health Impact Profile-14 (OHIP-14) questionnaire was used for the OHRQoL. The IBM SPSS Statistic 22.0 software program was used for the statistical evaluation of the study data. The plaque index and gingival index values were statistically higher in obese compared to normal weight individuals (p[removed]0.05). There was no statistically significant difference between the OHIP-14 total scores of the groups (p>0.05). Increased apparent plaque index and gingival index values in obese patients may adversely affect periodontal health.Öğe Twenty-Four-Month Clinical Comparison of Two Bulk-Fill and a Microhybrid Composite Restorations in Class II Cavities(Dennis Barber Ltd, 2021) Karaarslan, Emine Şirin; Bal, Fatma Aytaç; Buldur, Mehmet; Altan, HalenurObjectives: The aim of this study was to evaluate the clinical performance of two bulk-fill composite resins in Class II cavities for up to twenty-four months. Materials and Methods: In total 75 Class II restorations were made in 25 patients using two nanohybrid bulk-fill resin composites and a microhybrid composite. The restorations were evaluated at baseline and at 6, 12, and 24 months, using U.S. Public Health Service (USPHS) criteria. The restoration groups were compared using the Pearson chi-square test, and the Cochran Q-test was used to compare the changes across different time points within restorative materials (p<0.05). Results: Two patients who did not attend the appointments were excluded from the study, so 23 patients were evaluated with a 92% recall rate; at the end of the two-year follow-up, 66 restorations were evaluated. Three restorations underwent endodontic treatment and were deemed failures. The overall success rate was 96%. There were statistically significant differences between the three restorative resins in terms of color match parameter (p[removed]0.05). Conclusions: During the two-year follow-up period, the three composite resins showed similar clinical performance except for the color match parameter.Öğe Effects of radiotherapeutic X-ray irradiation on cervical enamel(Taylor and Francis Ltd., 2021) Deniz, Yeşim; Aktaş, Çağatay; Misilli, Tuğba; Çarıkçıoğlu, BurakPurpose Therapeutic radiation used for head and neck cancers mainly affects the cervical region of the tooth. To better understand the impact of therapeutic radiation on tooth, we aimed to examine the crystallinity, micro-morphology, and elemental composition of the cervical inner enamel located adjacent to the dento-enamel junction. Materials and methods Ninety-one specimens obtained from 16 impacted third mandibular molars were randomly divided into seven groups (0, 10, 20, 30, 40, 50, and 60 Gy irradiation groups). Energy-dispersive X-ray spectroscopy (EDX) and scanning electron microscopy (SEM) were performed after the irradiation by 6 MV photon energy. The X-ray diffraction (XRD) were conducted in every group before and after irradiation. Elemental compositions, and Ca/P, P/N, Ca/N atomic ratios were subjected to the Shapiro-Wilk normality test. All of the elements except Mg showed a normal distribution and were compared by the one-way ANOVA. The non-normally distributed Mg data and Ca/P, P/N, and Ca/N ratios were compared by the Kruskal-Wallis test. Results The results showed that widening in the interprismatic spaces were observed in the experimental groups subjected to 30 Gy and the following increased doses. In addition, there were no significant differences in C, O, Ca, P, N percentages between irradiated and non-irradiated groups (p > .05). An increase in atomic ratio of the Mg was detected after samples conducted by 60 Gy radiation dose (p < .05). The stoichiometric Ca/P, Ca/N, and P/N atomic ratios did not change by irradiation (p > .05). The XRD peaks of the inner enamel crystalline phase showed a slight decline in the 60 Gy radiation dose group. Conclusion Radiation effects begin to be seen after 30 Gy radiation dose groups. The widen interprismatic spaces seen obviously in 50 Gy and 60 Gy dose groups. Besides Mg ratio showed an increase in the 60 Gy dose group. But it should be thought that radiation caries is a multi-factorial disease that is in collaboration with various radiation-induced side effects.Öğe The Effect of Ph-cycling and Toothbrushing Simulations on Surface Roughness of Bulk-Fill Composites(Marmara University, 2021) Misilli, Tuğba; Gönülol, Nihan; Cabadağ, Özge Gizem; Almasifar, Lena; Dinç, DeryaObjective: This study aimed to compare surface roughness values (Ra) of different posterior composites after pH-cycling and toothbrushing simulation. Methods: Fifty disc-shaped specimens (8x2 mm) were prepared by using three bulk-fill composites [Filtek Bulk Fill Posterior (FBF), SonicFill 2 (SF), X-tra fil (XF)], a flowable [G-aenial Universal Flo (GF)], and a microhybrid composite [Filtek Z250 (Z250)]. After initial roughness (Ra0 ) measurements were performed with a contact profilometer, the samples were subjected to a pH-cycling model for 10 days and Ra1 values were recorded. Then, the samples were subjected to toothbrushing simulation for 4 min and final values (Ra2 ) were recorded. From each group, a representative sample was analyzed with an optical profilometer. The values were analyzed by two-way ANOVA with repeated measures on one factor (period) followed by Tukey’s test (p<0.05). Results: Significant differences were found among materials regardless of experimental periods. The lowest Ra values were determined in GF and Z250 groups. The highest value was obtained in SF, but this value was not statistically significant different from that obtained in XF group. Brushing procedure after chemical degradation led to an increase in surface roughness of all materials except FBF, which was not statistically significant. Conclusion: While Ra values showed differences depending on the materials, pH-cycling and toothbrushing simulation did not have a significant effect on these values.Öğe Effects of high temperature on dental restorative materials for forensic purposes(Springer, 2021) Çarıkçıoglu, Burak; Misilli, Tuğba; Deniz, Yeşim; Aktaş, ÇağatayThis study aimed to observe the efects of high temperature on diferent restorative dental materials by detecting changes in their microstructural and elemental composition. Disk shaped samples (10 mm diameter, 2 mm depth) were prepared from 8 dental materials (compomer, glass carbomer, ormocer, giomer, zinc reinforced glass ionomer (GI), silver-alloy reinforced GI, zirconia reinforced GI, and conventional GI). Scanning electron microscopy/Energy dispersive X-ray spectroscopy (SEM/EDS) was used to characterize sample surface structures and elemental composition. The same samples were also analyzed using X-ray fuorescence (XRF) to determine the trace element content. Each sample was placed in a porcelain furnace and exposed to 900 °C for 30 min. Observations of macroscopic changes in samples after exposure high temperature were recorded. The microstructural changes in sample surfaces after incineration were detected by SEM. The elemental compositions obtained before and after the incineration were compared after repeating the XRF and EDS analyses. Dental materials demonstrated specifc macroscopic changes and microstructural deteriorations detected by SEM images after exposure to high temperature. While several changes occurred in the elemental content of materials in terms of amount, the original elemental composition was preserved. The ability to distinguish dental materials by elemental analyses has had an important impact on the identifcation process.
