Yazar "Yuksel, Cihan" seçeneğine göre listele

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    A Case of Brucellosis Presenting with Infarction in the Spleen
    (Doc Design Informatics Co Ltd, 2022) Alkan, Sevil; Guclu-Kayta, Safiye Bilge; Vurucu, Servan; Akca, Anil; Yuksel, Cihan; Onder, Taylan; Sener, Alper
    Brucellosis may present with different clinical pictures due to its ability to involve various organs. Although splenomeg-aly can be seen as a result of spleen involvement in brucellosis, splenic infarction is rare. However, left upper quadrant pain may be observed when splenic infarct occurs. This case report presents a case of brucellosis with splenic infarct.
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    Decoding budget awareness: A multivariate analysis of generation Z undergraduates
    (Public Library Science, 2025) Gungor Goksu, Gonca; Eroglu, Erdal; Yuksel, Cihan; Kucukaycan, Durdane
    Understanding public finance and budget processes has become increasingly important for the younger generation in recent years. This knowledge enables Generation Z to participate more effectively in democratic life as informed citizens. However, there is limited research on Generation Z's awareness of public budgets in the existing literature. Therefore, the study addressed a significant gap in the public finance literature. We aimed to examine the determinants influencing the state budget awareness of Generation Z undergraduates by using the survey: Citizens' Budget Awareness and Effective Factors. Data was collected from 3,972 undergraduates across all disciplines enrolled in four Turkish state universities between December 2023 and April 2024. We conducted a multiple linear regression analysis to examine the data. The main results showed that being informed about allocated public revenues for which public services, the constitutional power of the purse, budgeting processes and budget-related transactions were the determinants that most influenced the budget awareness of the students. On the contrary, being informed about the connection between taxes and public services, the Public Financial Management and Control Law No. 5018, and the amounts of public revenues within the state budget were determined as the lowest determinants influencing their awareness. Based on our results, we mainly suggested that (i) comprehensive education programmes and interactive learning should be organised in universities by using digital tools, (ii) the link between public revenues and expenditures should be explained through awareness campaigns, and (iii) budget processes should be made more transparent and accessible.
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    Investigation of Therapeutic Efficacy of Intravesical Tigecycline Administration in Rats with Cystitis Induced by Extensively Drug-Resistant (XDR), Tigecycline-Sensitive Acinetobacter baumannii Strain
    (Mdpi, 2025) Yuksel, Cihan; Aliravci, Isil D.; Kosan, Murat; Esen, Sinem; Yenice Aktas, Sevinc; Kaya Terzi, Neslihan; Berber, Ahmet Ali
    Background: This study aimed to evaluate the therapeutic efficacy of intravesical tigecycline administration in a rat model of cystitis induced by a tigecycline-sensitive, extensively drug-resistant (XDR) Acinetobacter baumannii strain. Methods: Thirty-six female Wistar albino rats were inoculated intravesically with XDR A. baumannii to induce cystitis. Twenty-four rats that developed infection were divided into four groups: untreated control, saline irrigation, low-dose tigecycline (6.25 mg/kg), and high-dose tigecycline (25 mg/kg). Microbiological clearance was assessed via urine cultures on days 3 and 5. Bladder tissues were analyzed histopathologically and for genotoxicity using the Comet assay. Results: On day 5, microbiological clearance was significantly higher in tigecycline-treated groups compared to controls (p = 0.028). Histopathology revealed significantly more inflammation in the high-dose tigecycline group (p = 0.029). Genotoxicity was observed in both tigecycline groups, independent of dose (p < 0.05). Conclusions: Intravesical tigecycline demonstrated microbiological efficacy against XDR A. baumannii-induced cystitis. However, its inflammatory and genotoxic potential necessitates further preclinical evaluation.