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    Assessment of Calcaneal Morphology and Radiological Parameters in Haglund's Syndrome
    (Galenos Publ House, 2022) Buyukdogan, Kadir; Aslan, Lercan; Kaymaz, Burak; Yilmaz, Onur; Ayik, Gokhan; Mermerkaya, Musa Ugur
    Objective: To compare the radiological parameters of the normal population with the patients with Haglund's syndrome (HS) and to seek a correlation between pain scores and radiological parameters in patients with HS.Methods: Thirty-one patients surgically treated for HS (Haglund group) and 36 healthy subjects free of hindfoot pathology seen in consultation for any other foot pathologies (control group) were included in the study. Demographic data of the patients were acquired, and radiological measurements such as; Fowler Philip Angle (FPA), lateral talus-first metatarsal angle (LTFMA), and Calcaneal pitch angle (CPA) were recorded. The visual analog scale (VAS) and the American Orthopaedic Foot & Ankle Society (AOFAS) scores of the patients in the Haglund group were assessed.Results: Mean CPA, FPA, and LTFMA in the Haglund group were 23.88 +/- 4.6, 58.16 +/- 5.7, and 4.92 +/- 1.88, respectively, and the same recordings in the control group were 21.16 +/- 4.81, 59.1 +/- 4.3, and 4.25 +/- 2.57, respectively. CPA differences between Haglund and control groups were statistically significant (p=0.021). The average values of the VAS and AOFAS scores of the patients in the Haglund group were 8.45 +/- 1.06 and 47.4 +/- 7.58, respectively. There was no correlation between the scores and the radiological measurements of patients in the Haglund group.Conclusion: Radiological assessments are widely debated. Many studies support our results that measurements defined for the morphology of calcaneus are not associated with the Haglund's disease severity. Increase in the CPA is found to be related to HS. This may be explained by the extension of the calcaneus to irritate the Achilles tendon and cause heel pain.
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    Genetic diversity and population structure of Anatolian Hair goats, an ancient breed
    (Copernicus Gesellschaft Mbh, 2024) Demiray, Aylin; Gunduz, Zuhal; Ata, Nezih; Yilmaz, Onur; Cemal, Ibrahim; Konyali, Aynur; Semen, Zeynep
    This study aimed to investigate the genetic characterization and diversity of Hair goats from 10 regions using 20 microsatellite markers. A total of 522 alleles were observed. The INRA0023 locus exhibited the greatest number of alleles (48), while the DRBP1 locus had the highest effective allele number (16.27), and the BM1818 and DRBP1 loci had the highest polymorphic information content value (0.94). The expected heterozygosity value ranged from 0.85 (ILSTS011) to 0.94 (BM1818, SRCRSP15, and DRBP1). The Hair goat populations in Konya and Hatay displayed the lowest and highest allele numbers, with values of 10.40 and 16.25, respectively. The fixation index (FIS) values are significant in defining population structures and determining the extent of heterozygosity losses. The FIS values exhibited a range of 0.031 in Mu.gla to 0.226 in Burdur. A total of 107 unique alleles were identified in Hair goat populations. However, it is noteworthy that, out of all the alleles, only 25 had a frequency exceeding 5 %. The results indicate that the microsatellite markers utilized demonstrate sufficient levels of polymorphism, making them appropriate for efficiently investigating the genetic variability of Hair goat populations.
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    Local Anesthesia and Conscious Sedation Does Not Affect Patient's Mood and Anxiety Levels during Percutaneous Endoscopic Lumbar Diskectomy: A Prospective Study
    (Georg Thieme Verlag, 2021) Erken, H. Yener; Karaeminogullari, Oguz; Yilmaz, Onur; Mirel, Kerem; Ozer, R. Ozgur
    Background and Study Aims Undergoing a surgical procedure can be very stressful for patients and can lead to high anxiety levels during both the preoperative and the postoperative period. Levels of anxiety and fear may depend on multiple factors including the type of anesthesia to be used. The objective of this study is to evaluate whether patient's awareness of the surgical environment in the operating room under local anesthesia and conscious sedation (LACS) affects their mood and anxiety levels. Methods We performed a prospective study for a series of consecutive patients who underwent transforaminal percutaneous endoscopic lumbar diskectomy (PELD) for the treatment of lumbar disk herniation. The patients completed Profile of Mood States (POMS) and State-Trait Anxiety Inventory (STAI) forms in the preoperative period and in the early postoperative period. We divided the patients into two groups according to the type of anesthesia applied during surgery: LACS and general anesthesia (GA) groups. We compared the preoperative and postoperative POMS and STAI scores between groups and the change of these scores between the preoperative and postoperative periods in each group. Results In this study, we included 30 patients who underwent PELD between May and December 2019 and met the inclusion criteria. The GA group consisted of 16 patients and the LACS group consisted of 14 patients. In each group, POMS and STAI scores decreased in the early postoperative period compared with the preoperative period. We found no significant difference in percentage of POMS and STAI TX-1 score changes between the LACS and GA groups. Conclusion The results of our study show that patients' awareness of the surgical environment in the operating room under LACS does not significantly affect their mood and anxiety levels and patients do not seem to endure increased emotional stress during the PELD operation, as compared with PELD operation under GA.
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    No Decrease in Infection Rate with the Use of Local Vancomycin Powder After Partial Hip Replacement in Elderly Patients with Comorbidities
    (Springernature, 2020) Erken, H. Yener; Nusran, Gurdal; Karaguven, Dogac; Yilmaz, Onur; Kuru, Tolgahan
    Introduction The goal of this study was to evaluate the effects of local intra-wound vancomycin powder (VP) administration to decrease surgical site infections (SSIs), particularly in elderly patients with comorbidities, after having undergone partial hip replacement in the treatment of intertrochanteric (ITF) or femoral neck fractures (FNF). Methods We retrospectively reviewed patients who underwent partial hip replacement in the treatment of ITF or FNF in one year. We divided the patients into two groups. The non vancomycin-treated group received standard systemic prophylaxis only (1 gr cefazolin IV), while the vancomycin-treated group received 1 gr of VP in the surgical wound just before surgical closure in addition to the systemic prophylaxis. We included patients of 64 years or older who also had one or more comorbidities. We compared the post-operative SSI rates between the non vancomycin-treated group and the vancomycin-treated group. Results A total of 93 patients were included in the study. We detected post-operative wound infection in six patients (6.4%). The rate of SSI was found to be 5.7% in the vancomycin-treated group and 6.9% in the non vancomycin-treated group respectively, which showed no statistically significant difference (p:0.498). The incidence of SSI was statistically higher in the patients who had a follow-up in the post-operative intensive care unit than the patients who had not any follow-up in the intensive care unit. Conclusion Local application of VP in the surgical wound was found to be ineffective in reducing the incidence of SSI after partial hip replacement in elderly patients with comorbidities.
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    Tetracalcium phosphate treatment on experimental fracture model in rats
    (Turkish Joint Diseases Foundation, 2022) Kaymaz, Burak; Yilmaz, Onur; Tasova, Ali Osman; Anapa, Dogukan
    Objectives: This study aims to investigate the efficacy of tetracalcium phosphate (TTCP) on fracture healing in rat femurs. Materials and methods: Forty-two female Wistar Albino rats were randomized into two groups (Group 1 and Group 2, n=21 for each). The left femur of all animals was fractured by osteotomy after deep anesthesia with ketamine. Additional procedure was not applied to the rats in Group 1. Rats in Group 2, following osteotomy, were applied to the fracture line approximately 2 mL TTCP. The animals were sacrificed at Weeks 1, 2, and 3 after surgery (seven animals were sacrificed from each group each week) and the broken femurs were removed. The femurs were examined first radiographically and second histopathologically. Results: Radiologically, callus maturity and bone union increased with time in both groups. However, no significant differences were found regarding callus maturity and bone union in weekly comparisons (anteroposterior plain: p=0.53, p=0.37, p=0.42, lateral plain: p=0.26, p=0.42, p=0.87). Histopathologically, the fractures healed normally as the weeks progressed in both groups. The histological scores of Group 2 were higher at Weeks 1, 2, and 3. In the evaluation, no significant difference was found between the groups in terms of histological scores except for the first week (p=0.024, p=104, p=462, respectively). Conclusion: Although there was no statistically significant difference in the histological evaluation of both groups, except for the first week, the histological scores of Group 2, which underwent TTCP in all weeks, were higher. According to the results of this study, we believe that TTCP may be beneficial, particularly in the early stages of fracture healing.
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    The effects of carbogen and hyperbaric oxygen treatment on fracture healing in rats
    (Turkish Assoc Trauma Emergency Surgery, 2022) Menendi, Umman; Nusran, Gurdal; Kaymaz, Burak; Tiskaoglu, Ramazan; Yilmaz, Onur; Goret, Ceren Canbey
    BACKGROUND: Bone fractures and fracture healing are one of the most common problems among orthopedic surgeons. In this study, we investigated the effects of hyperbaric oxygen (HBO) and carbogen (C) treatment on fracture healing in the experimental animal model. METHODS: Twenty-four male Wistar-Albino rats were randomly divided into three groups as Group 1 (C inhalation therapy), Group 2 (HBO inhalation therapy), and Group 3 (control group), with eight rats in each group. HBO and C treatment were given to the rats in Group 1 and Group 2 1 week before the surgical procedure and 3 weeks after the surgical procedure. Following the surgical procedure, all rats were killed at the end of the 3rd week and the healing tissue in the fracture line was evaluated clinically, radiologically, and histopathologically. RESULTS: Although there were higher histopathological, radiological, and clinical scores in the HBO and C groups in terms of fracture healing compared to the control group, there was no statistically significant difference between the groups. CONCLUSION: There are many studies in the literature that examine the systemic and local effects of HBO and C treatments and show that they increase tissue oxygenation. Our study showed that HBO and C groups had no beneficial or harmful effects on fracture healing compared to the control group.