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Öğe Investigation of the Relationship Amongst Refraction, Keratometric and Pachymetric Measurements(Turkish Ophthalmological Soc, 2008) Eser, Ilker; Kaya, Vedat; Kucuksumer, Yasar; Yilmaz, Omer FarukPurpose: To investigate the relationship amongst refraction, central corneal thickness (CCT) and keratometric measurements. Methods: A retrospective study of the subjective refraction of 1022 eyes of 511 consecutive subjects who presented for refractive surgery evaluation was performed. Of the subjects, 241(48%) were male and 270(52%) were female. Mean age of male and female were 32.1 +/- 9 and 30.1 +/- 8.1 respectively. Javal Keratometer was used for keratometric measurements. CCT was obtained with DGH 4000B A-Scan/Pachymeter. The statistical forecasting methods used are Mann-Whitney U-test, Spearman Correlation, Wilcoxon signed rank test, Kruskal-Wallis methods as implemented in the software package SPSS version 11.5. A p-value of <0.05 was considered to be statistically significant. Results: The relation between the age of the patients and CCT, and keratometric measurements were not statistically significant (p=0.598, p=0.403) respectively. While CCT were higher in male (p=0.002), keratometric values were higher in female (p=0.0001). Spherical equivalent (SE) showed a correlation with CCT values (p=0.04), and a negative lineer correlation with the keratometric values (p=0.0001). While females were found to be more myopic, males were more hyperopic (p=0.0001). CCT were higher in the eyes those >+5.00 Diopter(D) (p=0.04), and keratometric values were higher in the eyes those less than -6.00 D (p=0.0001). Conclusions: Males had lower keratometric measurements and were more likely to be hyperopic or mix hyperopic astigmatism than female. Females were more mix myopic astigmatism than males. CCT was higher in high hyperops and low in high myopes. A negative linear correlation between the keratometric measurements and SE was found. We believe that, investigation of these parameters would be helpful in better understanding of the biometric characteristics of the eye and choosing the appropriate technique in refractive surgery.Öğe Isolates and antibiotic sensitivity of eighty culture-proven endophthalmitis cases from Istanbul(Karger, 2008) Eser, Ilker; Kapran, Ziya; Altan, Tugrul; Karatas, Meltem Ozel; Aydin, Derya; Okaygun, Eda; Yilmaz, Omer FarukPurpose: To investigate the spectrum of organisms causing endophthalmitis and their sensitivity to commonly used antimicrobial agents. Methods: Medical records of 80 consecutive patients treated at Beyoglu Eye Hospital for endophthalmitis from January 2001 to April 2006 were reviewed. Specimens were obtained from either the vitreous (93%, 81/87) or anterior chamber (7%, 6/87) during pars plana vitrectomy or vitreous tap, and were inoculated into blood culture bottles. A Kirby-Bauer disk diffusion test was performed to determine antibiotic susceptibility. The outcome measures included isolates identified and antibiotic sensitivity of the specimens. Results: Fifty-six of 87 (64.4%) isolates were Gram-positive organisms, 29 (33.3%) were Gram-negative organisms, and 2 (2.3%) were fungi. The most common organism group identified was coagulase-negative staphylococci in 26.4% (23/87). While vancomycin was active against all Gram-positive isolates tested (100%), ceftazidime had the highest susceptibility rate (100%) for Gram-negative organisms isolated. Conclusions: Although coagulase-negative micrococci predominated in this series, a high isolation rate for Gram-negative organisms was obtained. High susceptibility rates for ofloxacin make it an alternative to ceftazidime and vancomycin in both Gram-negative- and Gram-positive-derived endophthalmitis, respectively. Studies with larger series and additional antibiotics are needed to confirm these findings. Copyright (C) 2008 S. Karger AG, Basel.