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Öğe Long pentraxin-3 measured at late phase associated with GRACE risk scores in patients with non-ST elevation acute coronary syndrome and coronary stenting(Aves, 2012) Saygi, Serkan; Kirilmaz, Bahadir; Tengiz, Istemihan; Turk, Ugur Onsel; Yildiz, Hicran; Tuzun, Nurullah; Alioglu, EminObjectives: We analyzed pentraxin 3 (PTX3) levels and the relation of PTX3 levels with GRACE risk scores in 39 patients with non-ST elevation acute coronary syndrome (ACS) and stabile angina after stenting. Study design: Seventeen patients with ACS and 22 patients with stabile angina who underwent coronary stenting were included in the study. PTX3 levels were measured serially at admission, at the 8th hour and at the 24th hour after stenting. Results: While diabetes and hypertension were more frequent in the stabile angina group, leukocyte counts were significantly higher in the ACS group. PTX3 levels measured at the 8th hour were significantly higher in the ACS group compared to the stabile angina group (p=0.003). Strong correlations were observed between 24th hour PTX3 levels and GRACE scores calculated for risk of death and death/MI at admission (in-hospital/to 6 months), and for risk of death/MI at discharge to 6 months (R=0.571, p=0.01, R=0.564, p=0.01; R=0.558, p=0.02, R=0.512, p=0.03; R=0.653, p=0.004, respectively). Conclusion: The serum PTX3 levels may provide important information for the early risk stratification of patients with ACS who underwent coronary stenting.Öğe Prognostic Value of TIMI Frame Count in Patients with Metabolic Syndrome(Galenos Yayincilik, 2011) Mammadov, Vusal; Kinlmaz, Bahadir; Yildiz, Hicran; Dashdemirov, Rafael; Mahmudov, Rashad; Bakhshaliyev, AdilBackground: The aim of our study was to determine the coronary angiographic distribution and frequency of atherosclerotic lesions in the coronary arteries in patients with stable angina and metabolic syndrome (MS) as well as to assess the association of these lesions with TIMI frame count and combinations of MS criteria. Methods: Two hundred sixty-one patients aged 61.8 +/- 1.4 years were included in the study. All subjects were divided into three large groups: group 1 - patients with significant coronary artery stenosis and with MS (n= 148), group 2 -patients with significant coronary artery stenosis and without MS (n= 75), and group 3 -patients without significant coronary artery stenosis and without MS (n= 38). At the same time, the patients in group 1 were again divided into 3 subgroups based on the number of MS criteria. Arterial blood pressure (BP), waist circumference (WC), and levels of fasting glucose (FG), triglycerides (TG) and high-density lipoproteins (HDL) were measured in all patients. All subjects underwent coronary angiography and TIMI frame count was calculated. Results: According to the results in patients with stable angina with 5 criteria of MS, the TIMI frame count was significantly greater than in patients with stable angina with 3 and 4 criteria of MS. While in the group of patients with stable angina with 3 criteria of MS, the most frequent combination found was BP + WC + FG (28.3 +/- 6.2%), in patients with stable angina with 4 MS criteria, it was BP + WC + FG + HDL combination (48.0 +/- 7.1%). Conclusions: The TIMI frame count method is simple, inexpensive and broadly applicable and plays role in the understanding of the physiology and pathophysiology of coronary artery blood flow in patients with stable angina and MS. For this reason, the calculation of TIMI frame count in patients with stable angina and MS has an important place in selecting the treatment options and determining the prognosis of the disease.Öğe Reel syndrome: dislodgement of an active fixation lead(Turkish Soc Cardiology, 2013) Saygi, Serkan; Kirilmaz, Bahadir; Yildiz, Hicran; Ercan, Ertugrul[Anstract Not Available]