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    Clozapine and Aripiprazole-Induced Stuttering: A Case Report of Turner Syndrome with Schizophrenia
    (Kure Iletisim Grubu A S, 2016) Ertekin, Hulya; Ertekin, Yusuf Haydar; Sahin, Basak; Yayla, Sinan; Turkyilmaz, Ersin; Kara, Medine
    Turner Syndrome (TS) is the most common chromosomal anomaly in women. Its psychiatric manifestations have not been clearly defined. Occurrence of schizophrenia is higher in patients with TS than in the normal population. The literature has reported instances associating stuttering as a side effect of antipsychotic drugs, particularly clozapine-induced stuttering. We found only one case report describing aripiprazole-associated stuttering. In the present case report, we present a female patient with TS-diagnosed schizophrenia who had been treated with aripiprazole because she developed stuttering during treatment with clozapine and then developed dose-dependent stuttering with aripiprazole.
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    Depression and anxiety disorder comorbidity in patients with obstructive sleep apnea syndrome (OSAS)
    (Informa Healthcare, 2012) Bakim, Bahadir; Ertekin, Hulya; Karamustafalioglu, Oguz; Tekin, Atilla; Yavuz, Burcu Gokasan; Yayla, Sinan
    [Anstract Not Available]
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    Psychiatric Comorbidity in Patients with Conversion Disorder and Prevalence of Dissociative Symptoms
    (Routledge Journals, Taylor & Francis Ltd, 2015) Yayla, Sinan; Bakim, Bahadir; Tankaya, Onur; Ozer, Omer Akil; Karamustafalioglu, Oguz; Ertekin, Hulya; Tekin, Atilla
    The 1st objective of the current study was to investigate the frequency and types of dissociative symptoms in patients with conversion disorder (CD). The 2nd objective of the current study was to determine psychiatric comorbidity in patients with and without dissociative symptoms. A total of 54 consecutive consenting patients primarily diagnosed with CD according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, criteria who were admitted to the psychiatric emergency outpatient clinic of Sisli Etfal Research and Teaching Hospital (Istanbul, Turkey) were included in the study. The Structured Clinical Interview for DSM-IV Axis I Disorders, Structured Interview for DSM-IV Dissociative Disorders, and Dissociative Experiences Scale were administered. Study groups consisted of 20 patients with a dissociative disorder and 34 patients without a diagnosis of any dissociative disorder. A total of 37% of patients with CD had any dissociative diagnosis. The prevalence of dissociative disorders was as follows: 18.5% dissociative disorder not otherwise specified, 14.8% dissociative amnesia, and 3.7% depersonalization disorder. Significant differences were found between the study groups with respect to comorbidity of bipolar disorder, past hypomania, and current and past posttraumatic stress disorder (ps = .001, .028, .015, and .028, respectively). Overall comorbidity of bipolar disorder was 27.8%. Psychiatric comorbidity was higher and age at onset was earlier among dissociative patients compared to patients without dissociative symptoms. The increased psychiatric comorbidity and early onset of conversion disorder found in patients with dissociative symptoms suggest that these patients may have had a more severe form of conversion disorder.
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    Quality of Life and Depression in Schizophrenia Patients Living in a Nursing Home
    (Yerkure Tanitim & Yayincilik Hizmetleri A S, 2015) Ertekin, Hulya; Er, Mehmet; Ozayhan, Hatice Yardim; Yayla, Sinan; Akyol, Esra; Sahin, Basak
    Objective: Nursing homes are seen as alternative housing for patients with schizophrenia. However, it has not yet been established how suitable this accommodation is for schizophrenia patients. First aim of this study is to assess the quality of life and depression level in schizophrenic patients and compare this data with that of patients living with their families. Second aim is to assess factors related to the quality of living and depression state in all participants of this study. Method: This is a cross-sectional study conducted with patients presenting to the Psychotic Disorders Policlinic of the Beyhekim Psychiatric Clinic of Konya Training and Research Hospital consecutively between December 2012 and May 2013 who had received a diagnosis of schizophrenia according to DSM IV-TR. All participants were administered a sociodemographic data form, Brief Psychiatric Rating Scale (BPRS), Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), and Quality of Life Scale for Schizophrenia Patients (QLSSP). Results: CDSS scores were found to be significantly increased in schizophrenic patients living in nursing homes. Their QLSSP scores, including interpersonal relations, occupational role, mental symptoms, personal belongings/activity scores, and total scores were statistically significantly low. A significant negative correlation was observed between negative symptom levels and occupational area, mental findings, and the personal belongings/activity areas of quality of life. Between positive symptom levels and quality of life, only scores in the occupational area showed a significant negative correlation. A significant negative correlation between CSDS and QLS was observed in all areas. Conclusion: Quality of life and depression need to be evaluated in all schizophrenia patients, as they are conditions that significantly affect treatment and prognosis.
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    Yatarak tedavi gören bipolar bozukluk hastalarında dissosiyatif bozukluk eştanısı olan ve olmayan hasta gruplarının karşılaştırılması
    (Yusuf Haydar ERTEKİN, 2016) Bakım, Bahadır; Baran, Elif; Yayla, Sinan; Akpinar, Abdullah; Sengul, Hakan Serdar; Ertekin, Hulya; Güleken, Mehmet Diyaddin
    Giriş: Bu çalışmada dissosiyatif bozukluk (DB) eştanısı olan ve olmayan bipolar bozukluk (BB) hastalarının sosyodemografik karakteristiklerinin karşılaştırılması ve eştanı varlığının tedaviye etkisinin değerlendirilmesi amaçlanmıştır.Yöntem: BB tanısı ile Şişli Etfal Hastanesi Psikiyatri Kliniği’nde 2010-2011 yılları arasında yatışı yapılan ardışık 149 hasta çalışmaya alınmıştır. Hastalara SCID-D uygulanarak DB tanısı, SCID-I ile BB tanısı konmuş, sosyodemografik karakteristikleri, YMDÖ, HAM-D, KPDÖ, DYÖ puanları ve hastanede yatış süre ve sayıları incelenmiştir.Bulgular: 23 hastada (%15,4) başka türlü adlandırılamayan dissosiyatif bozukluk, 4 hastada (% 2,6) dissosiyatif kimlik bozukluğu, 1 hastada (%0,6) dissosiyatif amnezi tespit edildi. DB eştanısı olan BB hastalarının daha genç ve daha fazla oranda kadın olduğu belirlendi (sırasıyla p=0,002, p=0,015). DB eştanılı BB hastalarının DYÖ toplam puanının BB hastaların daha yüksek olduğu tespit edildi (p<0,001). Tüm örneklemde DYÖ toplam puanı ile hastanede kalış süresi arasında korelasyon bulunmuştur (p=0,001, Spearman r=0.336). Başvuru sırasında toplam HDÖ puanı eştanılı grupta anlamlı olarak daha yüksek (p=0,027), intihar maddesi hem başvuru hem taburculukta anlamlı olarak yüksek bulunmuştur (p<0,001 ve p=0,035). Başvuru esnasında KPDÖ puanlarından, halüsinatuar davranış maddesi eştanılı grupta yüksek bulunmuştur (p=0,019). YMDÖ puanlarından konuşma hız ve miktarı hem başvuru hem taburculukta (sırasıyla p=0,027, p=0,006), içgörü maddesi ise başvuru esnasında eştanının olmadığı bipolar hasta grubunda yüksek bulunmuştur (p=0,018).Sonuç: BB hastalarında DB eştanısı sorgulanmalıdır. DB eştanılı hastaların daha çok kadın cinsiyette ve daha genç yaşta olduğu, daha fazla depresyon puanlarına sahip olduğu; daha uzun süreli hastanede kalış süresine sahip olduğu bulunmuştur. Dissosiyasyon eştanısı varlığında, intihar girişim sayısı ve halüsinatuar davranışlarda artış görülebilir