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Pitfall of Steroid Treatment in Acute Demyelinating Encephalomyelitis Coexistent with Chickenpox: A Pediatric Case Report
(Çanakkale Onsekiz Mart Üniversitesi, 2019-08-15) Çokyaman, Turgay; Yaman, Ayhan; Damar, Çağrı
Primary infection of varicella zoster virus (VZV) causes to chickenpox and easily diagnosed with typical vesicular rashes. It is epidemic in pre-school and school age children since acute infection is very contagious. Infection usually heals spontaneously in healthy children. While post-infectious cerebellar ataxia is the most common complication of the central nervous system (CNS), it leads less likely to encephalitis, encephalomyelitis, meningitis, seizures and demyelinating diseases. Steroid and immune modulator treatments such as intravenous immunoglobulin (IVIG) or plasma exchange (PE) may be administered in the treatment of chickenpox related post-infectious demyelinating diseases. However, there is no clear data whether steroid treatment of demyelinating disease coexistent with chickenpox is suitable or not. In this article, we present a pediatric patient who acute demyelinating encephalomyelitis (ADEM) coexistent with chickenpox and given steroid treatment following IVIG and PE treatments.