Yazar "Voyvoda, Nuray" seçeneğine göre listele

Listeleniyor 1 - 2 / 2
  • Küçük Resim
    Öğe
    Feasibility of Diffusion-weighted Magnetic Resonance Imaging for Differentiating Idiopathic Granulomatous Mastitis From Malignant Breast Lesions
    (Galenos Publishing House, 2023) Rona, Günay; Arifoğlu, Meral; Voyvoda, Nuray; Kökten, Şermin; Çetin, Kenan
    Objective: Idiopathic granulomatous mastitis (IGM) is an inflammatory breast disease that is often challenging to differentiate from malignancy. This study investigated the role of diffusion-weighted (DW) magnetic resonance imaging in differentiating IGM from malignant breast lesions. Methods: This retrospective study included 82 female patients with IGM [with a mean age of 33.48 years, minimum (min): 22 - maximum (max): 58 years] and 85 female patients with breast cancer (with a mean age of 48.14 years, min: 31 - max: 79 years). The diagnoses of all patients were confirmed by biopsy, including 114 IGM lesions and 115 malignant lesions in the analysis. DW sequences were acquired with b-values of 0 and 1000 mm2/sec on a 1.5 T device. The apparent diffusion coefficient (ADC) values of the lesions were measured manually by placing multiple regions of interest of 50-100 mm2 in the target lesions and contralateral normal parenchyma. Results: The ADC values of both IGM (1.119±0.454x10-3 mm2/s) and malignant lesions (1066±0.610x10-3 mm2/s) were lower than those of normal parenchyma. The ADC values of the mastitis group were significantly higher than the ADC values of the carcinoma group (p=0.00). The inter-observer (r=0.627) and intra-observer (r=0.775) agreement of ADC measurements were strong. Conclusion: DW imaging is a useful noninvasive technique to differentiate between IGM and breast carcinoma.
  • [ X ]
    Öğe
    THE ROLE OF DIFFUSION-WEIGHTED MR IMAGING IN EVALUATING THE RESPONSE TO STEROID THERAPY IN IDIOPATHIC GRANULOMATOUS MASTITIS LESIONS
    (Istanbul Univ, Fac Medicine, Publ Off, 2022) Rona, Gunay; Arifoglu, Meral; Voyvoda, Nuray; Cetin, Kenan; Damgaci, Lale
    Objective: The aim of this study was to investigate the role of diffusion-weighted magnetic resonance imaging (DW MRI) with an apparent diffusion coefficient (ADC) map in evaluating the re-sponse to treatment of steroid-treated idiopathic granulomatous mastitis (IGM) lesions.Materials and Methods: This retrospective study included 99 le-sions of 58 female patients (average age: 32.91 years; range: 22-55 years) with biopsy-proven IGM. Patients were treated with oral and topical steroids. All pre-treatment and post-treatment MR exam-inations were evaluated. The maximal size of the masses and non-mass enhancement (NME) lesions were measured. Patients were classified as complete response (CR), partial response (PR), and non-response (NR) according to the dynamic contrast-enhanced (DCE) MR findings after treatment.Results: ADC values of areas occupied by IGM (0.933 +/- 0.317x10-3 mm2/sec) were lower than contralateral normal parenchyma (1.259 +/- 0.423x10-3 mm2/sec). Twenty-two (22.22%) of the lesions were in the NR group, 30 (30.30%) in the PR group, and 47 (47.47%) in the CR group. There was no significant difference between the pre-treatment ADC values in NR, PR, and CR groups (p=0.228). There was a significant difference between the pre-treatment and post-treatment ADC values in the PR groups (p=0.001).Conclusion: DW MR imaging in IGM is a useful method to monitor the response to treatment. However, it is not successful in predict-ing response to treatment.