Yazar "Volina, Emir" seçeneğine göre listele

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    Can Glypican-6 Levels Be Used to Determine Right Ventricular Remodeling After Non-ST Segment Elevation Myocardial Infarction?
    (Kare Publ, 2024) Kucuk, Ugur; Volina, Emir; Arslan, Kadir
    Objective: Myocardial infarction is associated with right ventricular (RV) remodeling. Glypican-6 (GPC6), a member of the membrane proteoglycan family, plays a significant role in cardiac remodeling. This study aims to determine if GPC6 can predict RV remodeling after percutaneous coronary intervention (PCI) in patients with non-ST segment elevation myocardial infarction (NSTEMI). Methods: The study enrolled 164 consecutive patients with NSTEMI and controls. It compared baseline plasma GPC6 levels, echocardiography, and laboratory parameters between the RV remodeling and non-RV remodeling groups with NSTEMI. Echocardiographic data were measured at baseline and at six months. Results: GPC6 levels were higher in the NSTEMI group 11.06 ng/mL (4.61-18.17) vs. 5.98 ng/ mL (3.81-9.83) compared to the control group in the initial phase. RV remodeling, defined as a >= 20% increase in RV end-diastolic area (RV EDA), was observed in 23 patients (30%). After six months, RV EDA increased significantly from baseline 18.68 +/- 1.20 cm2 2 vs. 24.91 +/- 1.08 cm(2),P < 0.001. GPC6 was a significant independent predictor of RV remodeling (hazard ratio [HR]: 1.546, 95% confidence interval [CI]: 1.056-2.245, P < 0.001). Receiver operating characteristic curve (ROC) analyses showed that GPC6 values > 15.5 ng/mL (area under the curve [AUC] = 0.828, sensitivity: 70%, specificity: 74%, P < 0.001) were strong predictors of RV remodeling. Conclusion: NSTEMI patients should be closely monitored for RV remodeling. GPC6 appears useful in detecting RV remodeling following NSTEMI in patients undergoing PCI.
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    Percutaneous Closure of the Atrial Septal Defect in a Patient with Dextrocardia and Situs Inversus Totalis
    (2021) Gazi, Emine; Barutçu, Ahmet; Aksit, Ercan; Volina, Emir; Demir, Cengiz
    Situs inversus totalis with dextrocardia and atrial septal defect is extremely rare. Different position and inversion types are required different closure techniques. We present a dextrocardia patient whose atrial septal defect was closed percutaneously. A 47-year-old female patient was referred for cardiological evaluation due to the diagnosis of situs inversus totalis and dextrocardia while preparing for gall bladder surgery. The patient’s heart was located on the right side, right heart chambers were dilated and a secundum-type atrial septal defect of 15 mm in width was detected. A 20 mm atrial septal defect closure device (Occlutech, GmbH) was placed and the defect was completely covered. In this case report, we defined technical differences and issues that should be considered when planning interventions in dextrocardia patients.
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    Öğe
    The Relationship between H2FPEF Score and Thrombus Burden in Patients with ST Elevation Myocardial Infarction
    (Wolters Kluwer Medknow Publications, 2022) Küçük, Ugur; Volina, Emir
    Background and Aim: The presence of intracoronary thrombus (ICT) is known to be associated with poor clinical outcomes, including death, in patients diagnosed with ST-segment elevated myocardial infarction (STEMI). Despite this, the predictors of ICT are still uncertain. The aim of our study was to investigate the relationship between thrombus burden (TB) and obesity (H), hypertension (H), atrial fibrillation (F), pulmonary hypertension (P), an age >60 years (E), and E/e’ > 9 (F) (H2FPEF) score in STEMI patients. Methods: One hundred consecutive STEMI patients were included in the study. Patients were divided into two groups according to the low TB (grades 0–3) and high TB (HTB) (grades 4 and 5) in comparison with the TB grade before percutaneous coronary intervention in coronary angiographic imaging. H2FPEF score was calculated for all patients. Results: The H2FPEF score was higher in the HTB group (2.94 ± 1.68 vs. 1.62 ± 1.15, P < 0.001). In STEMI patients, the red cell distribution width (odds ratio [OR]: 2.443, 95% confidence interval [CI]: 1.382–4.316; P = 0.002) and H2FPEF score (OR: 2.360, 95% CI: 1.447–3.847; P = 0.001) were independent predictors of HTB. H2FPEF score above a cutoff level of two predicted HTB with a sensitivity of 78% and a specificity of 50%. Conclusion: H2FPEF score may be used as a useful score in predicting HTB in STEMI patients. © 2022 International Journal of the Cardiovascular Academy.