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    Insomnia Catastrophizing and Affective Temperaments in Major Depressive Disorder
    (Korean Society of Sleep Medicine, 2024) Soylu, Hilal Sezer; Ertekin, Hülya; Uygur, Hilal; Akıncı, Erhan
    Background and Objective We aim to assess the role of affective temperaments, insomnia severity, sleep quality, and depressive anxiety symptoms in predicting catastrophizing insomnia in patients with major depressive disorder (MDD). Methods Our study employed a case-control design, involving 90 drug-free MDD patients and 90 healthy controls (HCs) with identical sociodemographic characteristics. Participants completed a comprehensive set of assessments, including the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), Insomnia Catastrophizing Scale (ICS), and Temperament Evaluation of Memphis, Pisa, Paris, San Diego Autoquestionnaire (TEMPS-A). Results Among the 90 MDD patients, 80% were female (n = 72), with a mean age of 32.2 ± 13.6 years. The MDD group exhibited significantly higher scores on the BDI, BAI, ISI, PSQI, ICS night, ICS daytime, and ICS total scores, along with depressive, cyclothymic, irritable, and anxious temperament scores, compared to the HCs (p < 0.001). Notably, the hyperthymic temperament showed no correlation with insomnia catastrophizing in either group. Our findings revealed that the ISI score was a predictive factor for the ICS night; age and ISI were predictive factors for the ICS daytime; and age, anxious temperament, and ISI were predictive factors for the ICS total in the MDD group. Conclusions The severity of insomnia, young age, and an anxious temperament were identified as positive predictors of insomnia catastrophizing. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright © 2024 The Korean Society of Sleep Medicine
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    The Effect of Accelerated Transcranial Magnetic Stimulation on Insomnia Severity and Sleep Quality in Patients With Treatment-Resistant Depression
    (Korean Society of Sleep Medicine, 2024) Uygur, Hilal; Tekdemir, Rukiye; Ertekin, Hülya
    Background and Objective Insomnia severity and poor sleep quality are linked with a poor response to depression treatments. Furthermore, they may heighten suicide risk, necessitating careful management and treatment of insomnia. This study explored how accelerated transcranial magnetic stimulation (aTMS) affects insomnia severity and sleep quality in patients with treatment-resistant depression (TRD). Methods This retrospective study included files from 28 patients with TRD who met specific inclusion and exclusion criteria. We assessed changes in insomnia severity and sleep quality by comparing scores before and after aTMS treatment. All patients underwent 50 sessions of intermittent theta burst stimulation over the left dorsolateral prefrontal cortex across 10 days. Results The mean age of the patients was 40.82±12.03 years. Before aTMS, the Insomnia Severity Index (ISI) score was 18.21±9.45, and the Pittsburgh Sleep Quality Index (PSQI) score was 12.85±4.75. After aTMS, ISI and PSQI scores improved to 5.75±6.70 and 6.75±5.01, respectively. The mean reductions in ISI and PSQI scores post-aTMS were 12.46 and 6.10, with Cohen’s effect sizes of 1.51 and 1.26, respectively. The sub-dimensions of subjective sleep quality and daytime dysfunction showed the most significant decreases, while sleep duration decreased the least. Improvements in all sleep parameters were statistically significant. Conclusions aTMS significantly alleviated insomnia severity and enhanced sleep quality in patients with TRD within just two weeks © (2024), (Korean Society of Sleep Medicine). All rights reserved.