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    COVID 19 Pnömonisi Olan Bir Hastada Olası Akut Pankreatit
    (2021) Alkan, Sevil; Yılmaz, Mustafa; Uyar, Cemile; Yıldırım, Ali Cihat; Demıray, Emıne Kubra Dındar
    Akut pankreatit (AP); bazen ilaç veya toksin yan etkisine, safra kesesi taşlarının pasajı veya sıkışmasına, viral enfeksiyonlara, alkol kullanımına, bazı metabolik bozukluklara, otoimmün hastalıklara bağlı olarak gelişebilir. İlk vakanın tespit edildiği Aralık 2019 tarihinden itibaren Korona virüs hastalığı 2019 (COVID-19) enfekte vaka sayılarının artması ile hastalığın sadece akciğer enfeksiyonu olarak değil, farklı klinik tabloları da bildirilmeye devam etmiştir. Sık karşılaşılan COVID-19 semptomları solunumsal semptomlar olsa da bazen solunum dışı semptomlar da gelişebilir. Bulantı, kusma, karın ağrısı ve diyare gibi gastrointestinal (GI) sistem semptomları ile gelen hastalar olabilir. Çok nadir de olsa pankreatit ile gelen hastalar olabilir. Bu vaka sunumunda; 66 yaşında, başvuru şikayeti karın ağrısı olan, COVID-19 ilişkili olası AP tanısı alan bir olguyu sunmayı amaçladık.
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    Evaluation of candidemia risk factors and Candida species distribution in intensive care units among patients with and without COVID-19
    (Saudi Med J, 2024) Uyar, Cemile; Yildiz, Emel; Genc, Ozlem; Ak, Oznur; Kocak, Emel; Alkan, Sevil; Balci, Canan
    Objectives: To assess the risk variables related to the types of candidemia for each patient, who was admitted into the intensive care unit regardless of the patient with or without complete diagnosis of COVID-19, during the period of March 2019 to December 2022. Methods: The evaluation comparison of demographic and clinical data of COVID-19 positive and negative patients with candidemia confirmed in blood, 113 cases were assessed. Variables such as gender, age, age of hospitalization, history of hospitalization, concurrently infection, The acute physiology and chronic health evaluation -II scores, comorbidity checking, intubation, central venous catheter use, parenteral nutrition use, steroid use, antibiotic use, lymphopenia, and laboratory variables were evaluated. Candida species distribution, antifungal susceptibility in blood culture were determined. Results: Coronavirus disease -19 was present in 62.8% of cases confirmed candidemia, and these cases were significantly different from COVID-19 negative cases. Significance was found in more intubation, central venous catheter use, parenteral nutrition, and steroid therapy in Group 2. There was no significance with species distribution and associated infection. In total, COVID-19 positive had higher hemoglobin, aspartate aminotransferase, alanine transaminase, and white blood cell levels, which may be associated with the possibility of revealing and controlling candidemia. Conclusion: Candida albicans and Candida Parapsilosis ( C. parapsilosis ) are the species seen in infected COVID-19 patients, while C. parapsilosis and Candida tropicalis are found in non-COVID-19 ones. Risk factors were intubation, parenteral nutrition, central venous catheter, and steroid in the COVID-19 group.
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    GEBELERDE HEPATİT B ENFEKSİYONU TARAMASININ ÖNEMİ
    (Aksaray Üniversitesi, 2022) Demiray, Emine Kübra Dindar; Alkan, Sevil; Uyar, Cemile
    Dünya üzerindeki kronik hepatit olgularının %90-95’inin hastalıklarının farkında olmadığı bilinmektedir. Bu nedenle de hem kendilerindeki mevcut hastalık ilerlemekte hem de virüsü başka kişilere bulaştırmaktadırlar. Maternal HBsAg pozitif olan kadınlarda Gestasyonel Diabetis Mellitus, Gebeliğe bağlı intrahepatik kolestaz, erken doğum ve neonatal asfiksi riskleri nispeten artmaktadır .Bu sebeple HBsAg pozitif gebelerin doğumdan önce saptanması da büyük önem taşımaktadır. Ulusal yenidoğan HBV aşılamasının uygulanmaya başladığı 1998-1999 yılları arasında doğmuş olan gebelerin (20-21 yaş)ise bu dağılım tablosunda toplam olguların sadece %2.8’ini oluşturduğu, 2000-2003 doğumluların % 0.8‘ini 2004 ve sonrasında doğmuş gebelerin ise tüm HBsAg pozitif gebelerin sadece %0.5 ‘ini oluşturduğu saptanmıştır. Bu olumlu değişiklik, ulusal HBV aşılama programı sonrası olmuştur.Aşılamanın ve taramanın tüm yaş gruplarında olduğu gibi gebelerde yakın takibi önem arz etmektedir
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    Global bibliometric analysis of publications on COVID-19 in newborns
    (Cukurova Univ, Fac Medicine, 2023) Barutçu, Adnan; Alkan, Sevil; Barutçu, Saliha; Özdener, Fatih; Uyar, Cemile
    Purpose: Though there are gaps in the relationship between COVID-19 and newborns no bibliometric analysis was published until now. This study aims to perform a bibliometric overview of literature of the relationship between newborns and COVID-19 in order to guide future studies addressing the same problem.Materials and Methods: Web of science was used to scan the published literature on newborns & COVID-19 by searching studies with and bibliometric networks were visualized by VOSviewer software. COVID-19, SARSCoV-2, 2019-nCoV with perinatal, neonatal, newborn and infant were used as keywords.Results: 912 keyword-coherent publications were found in the period 1970-2021, (491; 54.43% high quality studies) mostly about pediatrics and obstetrics gynecology with most frequent keywords; COVID-19, Sars-Cov-2, Pregnancy, Vertical Transmission and Newborn. United States, China, England and Italy have the highest number of studies as well as highest number of citations. COVID- 19 on neonatal outcomes and pregnancy had highest citation. Conclusion: Scientific network monitoring via bibliometric analysis is crucial and proved highly beneficial during COVID-19 crisis. Despite the articles on COVID- 19 & newborn have a decent number of citations, it vastly lower compared to the other studies about adults or clinical features and should be increased while it is still early.
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    Research trends and hotspots of osteoarticular involvement in brucellosis
    (University of Tabriz, 2022) Uyar, Cemile; Alkan, Sevil; Tahmaz, Alper
    Human brucellosis causes a variety of clinical symptoms and osteoarticular involvement is the most common involvement. We conducted a bibliometric analysis study on osteoarticular involvement in brucellosis. The study's aim was to investigate the impact of publications in this field and to discover research development and clusters. We used the Web of Science (Wos) database to obtain the data. The titles, document types, publication years, authors, organizations, keywords, abstracts of each record, H-index, and citations were analyzed. We analyzed 642 documents (research articles and review articles). 83.178% of them were published in Science Citation Index Expanded (Sci-Expanded) indexed journals. English (88.785%) was the most preferred language. Researchers from 70 countries contributed to the growth of scientific studies. Turkey was ranked first with a total of 177 publications. The United States of America (11.059%), Peoples' Republic of China (8.411%), Iran (6.698%), and Spain (6.698%) were the top five countries according to the number of publications. The publications were cited 11118 times (17.32 per item) and the mean of the H-index was 51. The publications published between 2000-2009 received the highest number of citations and had the highest H indexes. H indexes and citation numbers of publications have decreased since 2010. This is the first report that shows the trends of osteoarticular involvement in brucellosis. In conclusion, financial support for scientific studies in regions where brucellosis is endemic may increase the number of articles to be published in the future from these regions. © 2022, Published by University of Tabriz.