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    Assessment of toxicity and oxidative stress induced by rare earth oxide nanoparticles in brine shrimp (Artemia salina)
    (Elsevier Ltd, 2024) Unal, Ilkay; Erturk Gurkan, Selin; Aydogdu, Burcu
    This study meticulously explored the oxidative stress effects induced by lanthanum (III) oxide (La2O3), erbium (III) oxide (Er2O3), and yttrium (III) oxide (Y2O3) nanoparticles on Artemia salina, with the objective of evaluating the environmental toxicity of rare earth oxide nanoparticles. The characterization of the nanoparticles was conducted using a suite of advanced techniques, including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), dynamic light scattering (DLS), and zeta potential analysis. Artemia salina, a widely recognized model organism in ecotoxicological research, was exposed to these nanoparticles under meticulously controlled laboratory conditions. The investigation focused on quantifying oxidative stress markers, such as reduced glutathione (GSH), malondialdehyde (MDA), and antioxidant enzymes including catalase (CAT), superoxide dismutase (SOD), and glutathione-S-transferase (GST). The findings revealed significant alterations in these biomarkers, indicating nanoparticle-induced oxidative stress, which varied according to the type of nanoparticle and the duration of exposure. © 2024 Elsevier Ltd
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    Öğe
    The effects of biosynthesized silver nanoparticle on oxidative stress parameters in model organism Artemia salina (Linnaeus, 1758)
    (Taylor & Francis Inc, 2024) Unal, Ilkay; Gurkan, Selin Erturk
    Evaluation of the effects of nanomaterials in various habitats and living groups is increasing with in vitro and in vivo studies. This study aims to describe a biological procedure to synthesize silver nanoparticles using an extract of Marrubium astracanicum and to determine the aquatic environment's oxidative stress on Artemia salina. Silver nanoparticle formation was visually observed with color change. Its structural properties, such as size, shape, morphology, and stability, were characterized by UV-Vis spectrophotometer, TEM, SEM, XRD, and DLS analyses. TEM image showed that the synthesized AgNPs have a size of between 20 and 50 nm. The effects of biosynthesized silver nanoparticles at different concentrations (control,0.2, 1, 5, 10, 25, and 50 mg/mL) and exposure times (24, 48 and 72 h) on total glutathione (GSH) and lipid peroxidation levels (MDA) were investigated on the Artemia salina organism, which is one of the most common saltwater organisms frequently used in ecotoxicity tests.