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    Schwannoma of the Eyelid
    (Çanakkale Onsekiz Mart Üniversitesi, 2014) Oltulu, Pembe; Oltulu, Refik; Turan, Meydan; Erşan, İsmail
    A 21-year-old woman presented with a nodular lesion, a history of a slowly enlarging, mobile, 2 cm in diameter, located on the nasal region of the left upper eyelid. She reported no history of previous trauma or surgery regarding the lesion. The mass had a cystic appearance and cartilaginous consistence; it was non-adherent to the skin or the underlying tissue. Excisional biopsy revealed the characteristic histopathologic features of a schwannoma. After complete excision, there was no recurrence at 6-months follow-up. Schwannomas usually occur as single and slow growing benign tumours thought to arise from the Schwann cells of the peripheral nerves involving commonly the cranial and spinal nerve roots. These tumors preferentially involve sympathetic, cervical, and vagus nerves. Other sites involved include the face, neck, scalp and hands. Examples have been recorded in the tongue, palate and larynx. In most cases, while Schwannoma is sporadically manifested as a single benign neoplasm, the presence of multiple Schwannoma is usually indicative of neurofibromatosis–2. Our patient had isolated eyelid Schwannoma with no family history or clinical findings of neurofibromatosis–1 or neurofibromatosis–2. Schwannomas of ophthalmic interest are rare, although they have been reported in relation to the orbit (1% of orbital tumors), and infrequently to the uveal tract, conjunctiva and sclera. Eyelid schwannoma is a rare, slowly growing, benign neoplasm. This case suggest that schwannomas should be included in the differential diagnosis of any eyelid mass lesions and that accurate histological diagnosis and complete excision should be carried out in these cases.