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    Comparison of the Short-Term Efficacy of Physical Therapy in Subacromial Impingement Syndrome Patients with Stage I and II Magnetic Resonance Imaging Findings
    (Turkish League Against Rheumatism, 2011) Hakguder, Aral; Tastekin, Nurettin; Birtane, Murat; Uzunca, Kaan; Zateri, Coskun; Sut, Necdet
    Objectives: In this study, we compared the efficacy of a combined physical therapy program between stage I and II subacromial impingement syndrome patients. Patients and methods: Forty-three patients with subacromial impingement syndrome assessed as stage I and II according to the magnetic resonance imaging (MRI) findings were included in the study. Constant's and University of California Los Angeles Shoulder Scales were used to evaluate pain and function. Pain levels at rest, during motion and while asleep were also scored by visual analog scale before treatment, after treatment and at one month after treatment. Improvements within and between the groups were assessed. A physical therapy program consisting of ultrasound, superficial heat therapy and transcutaneous electrical nerve stimulation modalities combined with an appropriate exercise program was applied to both groups during half monthly sessions. Results: The between-groups comparisons performed after treatment and during follow-up revealed no significant difference in terms of the outcome measures assessed. Conclusion: Stage II patients responded to the physical therapy program as well as patients with stage I MRI findings.
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    Does Gender Difference Effect Radiation-Induced Lung Toxicity? An Experimental Study by Genetic and Histopathological Predictors
    (Radiation Research Soc, 2022) Cosar, Rusen; Ozen, Alaattin; Tastekin, Ebru; Sut, Necdet; Cakina, Suat; Demir, Selma; Parlar, Sule
    Several studies have reported differences in radiation toxicity between the sexes, but these differences have not been tested with respect to histopathology and genes. This animal study aimed to show an association between histopathological findings of radiation-induced lung toxicity and the genes ATM, SOD2, TGF-beta 1, XRCC1, XRCC3 and HHR2. In all, 120 animals were randomly divided into 2 control groups (male and female) and experimental groups comprising fifteen rats stratified by sex, radiotherapy (0 Gy vs. 10 Gy), and time to sacrifice (6, 12, and 24 weeks postirradiation). Histopathological evaluations for lung injury, namely, intra-alveolar edema, alveolar neutrophils, intra-alveolar erythrocytes, activated macrophages, intra-alveolar fibrosis, hyaline arteriosclerosis, and collapse were performed under a light microscope using a grid system; the evaluations were semi quantitatively scored. Then, the alveolar wall thickness was measured. Real-time quantitative reverse transcription PCR (RT-qPCR) was used to determine gene expression differences in ATM, TGF-beta 1, XRCC1, XRCC3, SOD2 and HHR2L among the groups. Histopathological data showed that radiation-induced acute, subacute, and chronic lung toxicity were worse in male rats. The expression levels of the evaluated genes were significantly higher in females than males in the control group, but this difference was lost over time after radiotherapy. Less toxicity in females may be attributable to the fact that the expression of the evaluated genes was higher in normal lung tissue in females than in males and the changes in gene expression patterns in the postradiotherapy period played a protective role in females. Additional data related to pulmonary function, lung weights, imaging, or outcomes are needed to support this data that is based on histopathology alone. (C) 2022 by Radiation Research Society
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    Evaluation of Handwashing Behaviors and Analysis of Hand Flora of Intensive Care Unit Nurses
    (Elsevier Science Inc, 2011) Findik, Ummu Yildiz; Otkun, Muserref Tataman; Erkan, Tulay; Sut, Necdet
    Purpose The aim of this study was to evaluate the handwashing behaviors of intensive care nurses based on personal statements, and to identify the microorganisms represented in the hand flora preshift and postshift. Methods This prospective study was performed with 60 intensive care nurses between January and December 2008, at a training and research hospital at a university in Turkey. Samples were taken from the hands of the nurses for bacteriological culture, using the bag-broth method, at the beginning and end of the shift. The samples were cultured aerobically and the colonies that grew were counted and identified. The nurses completed a self-report questionnaire, and their answers were evaluated. Results The frequency of handwashing by participants during each shift was 32.8 +/- 13.9. Overall, 65% of the nurses preferred alcohol-based antiseptic solutions for handwashing, 95% used paper towels to dry their hands, and 98.3-100% of the nurses washed their hands after performing care procedures. The Escherichia coli and coagulase negative Staphylococcus species were found to be at significantly higher levels in the postshift hand culture samples when compared to the preshift hand culture sample values. Enterobacter cloacae was the only species found in the postshift hand culture samples of the nurses. Conclusions The number of colonies of the microorganisms in the hand flora of the nurses increased postshift. The handwashing behavior of intensive care nurses must be improved as they nurse critical patients. [Asian Nursing Research 2011;5 (2):99-107]
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    Growth of Escherichia Coli in Atracurium, Rocuronium, Mivacurium, Cisatracurium, Pancuronium, and Vecuronium
    (Aves Yayincilik, Ibrahim Kara, 2009) Memis, Dilek; Otkun, Mueserref; Bahar, Meral; Sut, Necdet
    Objectives: We studied in vivo growth of Escherichia coli in atracurium, rocuronium, mivacurium, cisatracurium, pancuronium, and vecuronium. Patients and Methods: The pathogen was exposed to atracurium, rocuronium, mivacurium, cisatracurium, pancuronium and vecuronium for 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, and 24 h at room temperature, respectively. Results: The mean colony counts of Escherichia coli after exposure to rocuronium was significantly lower than the counts after exposure to atracurium, mivacurium, cisatracurium, pancuronium and vecuronium (p=0.002, 0.000, 0.000, 0.001, and 0.002, respectively). No significant difference was found with respect to the mean colony counts with atracurium, mivacurium, cisatracurium, pancuronium and vecuronium (p<0.05). Conclusion: Rocuronium had more powerful antimicrobial effects than the other neuromuscular agents.