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Öğe Are Small Adrenal Incidentalomas Solely a Radiological Finding?(Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, 2015) Eroglu, M.; Erbag, G.; Turkon, H.; Binnetoglu, E.; Ozkul, F.; Gunes, F.; Sen, H.Objective: The criterium defining the threshold size of adrenal incidentaloma (AI) is a size greater than 1cm diameter. However, data concerning AI1cm in diameter is scant. The aim of this study was to evaluate the function of adrenal masses1cm and to compare them with adrenal masses>1cm. Materials and Methods: The study included 130 consecutive patients with AI (38 and 92 AI at 1cm and >1cm, respectively). The patients were evaluated according to demographic and hormonal characteristics. Results: The prevalence of SCS was 5.3 and 12% in AI1cm and >1cm diameter, respectively. Hyperaldosteronism was found only in patients with >1cm AI. Pheochromocytoma were not found in either group. Patients with >1cm AI had a higher prevalence of SCS and primary hyperaldosteronism than patients with 1cm AI, but the difference was not significant. The prevalence of diabetes and hypertension was high both in non-functional AI with 1cm and >1cm patients and showed no significant difference between the 2 groups. Conclusion: Our study is the first to focus on the clinical and hormonal characteristics of patients with 1cm AI. Those with AI1cm harboured SCS, as was the case for AI>1cm. Similar to AI>1cm, non-functional AI1cm also had a higher prevalence of diabetes and hypertension.Öğe IMPULSIVITY AND ATTENTION DEFICIT-HYPERACTIVITY SYMPTOMS AMONG FEMALE PATIENTS WITH OBESITY(Cambridge Univ Press, 2013) Karaahmet, E.; Altinbas, K.; Sen, H.; Gunes, F.; Bakim, B.; Konuk, N.[Anstract Not Available]Öğe Investigation of endocrine and immunological response in fat tissue to hyperbaric oxygen administration in rats(C M B Assoc, 2016) Sen, H.; Erbag, G.; Ovali, M. A.; Oztopuz, R. O.; Uzun, M.Though HBO treatment is becoming more common, the mechanism of action is not fully known. The positive effects of HBO administration on the inflammatory response is thought to he a possible basic mechanism. As a result, we aimed to research whether endocrine and immunological response of tat tissue changes in rats given HBO treatment model. This research was carried out on Wistar albino rats, they were treated with hyperbaric Oxygen therapy. Their fatty tissue were taken from the abdomen, gene expression of the cytokines and adipokines mTere analyzed with Real time PCR method. When the gene expression of hormones and cytokines by fat tissue was examined, the leptin, visfatin, TNF-alpha, IL-1 beta and IL-10 levels in the HBO treatment group were statistically significantly increased compared to the control group (1)=0.0313, p=0.0156, p=0.0156, p=0.0156, p=0.0313). In conclusion, in our study we identified that HBO administration affected the endochrinological functions of fat tissue.Öğe Relationship between betatrophin levels and metabolic parameters in patients with polycystic ovary syndrome(C M B Assoc, 2016) Erbag, G.; Eroglu, M.; Turkon, H.; Sen, H.; Binnetoglu, E.; Aylanc, N.; Asik, M.To evaluate the status of serum betatrophin levels and potential relations between metabolic parameters and betatrophin levels in patients with polycystic ovary syndrome. We included patients newly diagnosed with PCOS in our study. Fifty-seven female patients (30 patients with PCOS and 27 healthy control subjects) were enrolled in this study. Serum betatrophin levels were measured using a betatrophin enzyme-linked immunosorbent assay kit. Insulin resistance was calculated using the homeostasis model of the assessment-insulin resistance index formula. The betatrophin level was 1538,85 ng/L in the patient group and 2440,46 ng/L in the control group, and the difference was statistically significant (p=0.003). A significantly negative correlation was found between betatrophin level and insulin, HOMA-IR, and BMI. Betatrophin levels in patients with PCOS are lower than those without PCOS and inversely related to insulin resistance.Öğe The Importance of Education in Diabetic Foot Care of Patients with Diabetic Neuropathy(Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, 2015) Sen, H. M.; Sen, H.; Asik, M.; Ozkan, A.; Binnetoglu, E.; Erbag, G.; Karaman, H. I. O.Objective: Our aim is to research the effect of the knowledge and routine gained from the diabetic foot (DF) care education program given to patients with Type 2 Diabetes Mellitus (DM) with diabetic neuropathy. Materials and Method: A total of 104 patients with Type 2 DM and diabetic neuropathy participated in a survey to evaluate standards of DF care, and knowledge of and behavior relating to personal care. The difference in knowledge and personal care between the group who had received education on diabetes and the group who had not was researched. Results: A total of 42.3 % of patients reported receiving education about diabetes. The education for Type 2 DM patients increased the frequency of attending yearly check-ups (p:0.028), and helped develop the habit of having doctors check their feet (p:0.004). When comparing the daily practice of those who had received education about DF care with those who had not, positive effects of education were seen in all questions evaluating foot care, nail care and choice of shoe. The statistical analysis proved that the educated group were significantly better in terms of foot care such as using moisturizer (p:0.002) and using insoles (p:0.042). Conclusion: Our study reveal that educating diabetic patients about foot care is an effective method to develop their knowledge. However we observed that this education is not provided to all diabetic patients. We believe that every diabetic patient should receive education from the moment of diagnosis and repeated education during check-ups by doctors will increase effectiveness.
