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Öğe A Bibliometric Study on Buruli Ulcer Based on the Web of Science Database(Sage Publications Inc, 2023) Alkan, Sevil; Sahinoglu, Mustafa SerhatBuruli ulcer is caused by Mycobacterium ulcerans, a skin infection that occurs mostly in people living in the developing economies of Africa and is considered a neglected tropical disease by the World Health Organization (WHO). Left untreated, it can lead to chronic wounds and loss of limbs. This disease is one of the target diseases of the WHO, and there are very limited bibliometric studies published on this subject. Also, no similar study using the Web of Science Core Collection was found in the available literature. The aim of this study was to evaluate the bibliometric analysis of the literature on Buruli ulcers. For data visualization and analysis, the open-source visualization program Biblioshiny (version 2.0) was used. Although most publications are from Ghana, the United States, and European countries have also made significant contributions. The number of publications has increased especially since 2016. The most preferred keywords in the publications were treatment, diagnosis, and transmission routes. This is the first bibliometric analysis that examines the trend of scientific publications on Buruli ulcer that have been indexed in the Web of Science. Our findings have the potential to be used by academics to improve their research.Öğe Association between chronic hepatitis B virus infection and premature ejaculation in a Turkish population(Taylor & Francis Ltd, 2024) Evlice, Oguz; Bulbul, Emre; Sahinoglu, Mustafa Serhat; Taspinar, Ebru; Alkan, SevilAim: To investigate the relationship between hepatitis B virus (HBV) infection and premature ejaculation (PE) in a Turkish Population. Materials/methods: A total of 147 patients with chronic HBV infection and 150 healthy volunteers were included in the multi-center case-control study. PE was evaluated using the five-item Premature Ejaculation Diagnostic Tool (PEDT) validated in Turkish men. Results: The presence of PE was significantly higher in the HBV-infected group compared with the control group (32.7 vs 18.7%; p = 0.006). The METAVIR fibrosis score was significantly higher in the PE group than in the non-PE group (p = 0.028). Discussion & conclusion: PE is more common in HBV-infected patients than in healthy individuals. Chronic liver damage is more common in HBV-infected patients with PE.Öğe Evaluation of Quality of Life, Anxiety and Depression in People Living with HIV(Galenos Publ House, 2024) Sahinoglu, Mustafa Serhat; Kandemir, Fatma Ozlem; Alkan, Sevil; Evik, Guliz; Turkegun-Sengul, MerveIntroduction: The topic of health-related quality of life (HRQoL) has become increasingly significant due to the advancements in antiretroviral therapies and the increase in life expectancy among individuals living with people living with human immunodeficiency virus (PLWH). We aimed to ascertain the levels of anxiety, depression, and HRQoL in PLWH. Materials and Methods: This study was conducted between March and November 2020 at Mersin University Hospital, a tertiary level hospital in Turkey. The HRQoL was evaluated using the 36-Item Short Form Health Survey (SF-36), while depression and anxiety were assessed using the Beck Depression Scale (BDS) and Beck Anxiety Scale (BAS), respectively. Based on the univariate analysis results, all candidate variables with a p value of<0.25, which may clinically be a risk factor for SF-36 physical component summary (PCS) and mental component summary (MCS), were selected and evaluated using multivariate logistic regression analysis. Results: The PCS and MCS scores were significantly lower (p<0.05), while the BDS and BAS scores were significantly higher (p<0.05) in the PLWH group. The depression and anxiety rates were 31.7% and 22.1%, respectively. Anxiety and depression adversely affected the quality of life (p<0.05). Multivariate analysis demonstrated that female sex [p=0.040, odds ratios (OR): 3.115, 95% confidence interval (CI): 0.109-0.949 for PCS; p=0.033, OR: 4.200, 95% CI: 0.063-0.893 for MCS], missed outpatient clinic appointments (p=0.025, OR: 2.397, 95% CI: 1.114-5.159 for PCS; p=0.017, OR: 3.407, 95% CI: 1.250-9.282 for MCS), depression (p=0.001, OR: 3.479, 95% CI: 1.612-7.508 for PCS; The risk on MCS could not be calculated), and anxiety (p=0.042, OR: 2.597, 95% CI: 1.035-6.518 for PCS; p=0.001, OR: 6.74, 95% CI: 2.153-21.124 for MCS), were factors related to both low PCS and MCS scores. Conclusion: High anxiety and depression levels among the PLWH in our study had an adverse impact on their HRQoL.Öğe Investigating the articles on HIV/AIDS from Turkey with bibliometric methods(Termedia Publishing House Ltd, 2023) Alkan, Sevil; Sahinoglu, Mustafa SerhatIntroduction: The purpose of the study was to determine the volume and extent of general human immunodeficiency viruses (HIV)/acquired immunodeficiency syndrome (AIDS) research in Turkey as well as the coverage of national HIV/AIDS research agenda. Material and methods: Web of Science (WoS) Core Collection advanced search engine was applied to conduct bibliometric search. HIV or AIDS or HIV/AIDS or Human immunodeficiency virus or HIV-1 or HIV-2 or acquired immunodeficiency syndrome and Turkey were used as search key words. In addition, the study included Language = English, Document area = medicine and Document type = Article. We also selected science citation index expanded (SCI-EXPANDED) and social sciences citation index (SSCI) as Web of Science indexes. The data in WoS improved all information on publications, including fields of study, institutions, group authors, funding agencies, journals, citations, and co-authorship. Results: In total, 313 articles were found. The first document was published in 1996, and 310 (99%) papers were published in the last 20 years. The documents were mostly (62.300%) published in science citation index expanded (SCI-EXPANDED) indexed journals. Most of the publications were from medicine general internal (33.866%) area. The top-ranked affiliations from Turkey in HIV/AIDS research were Istanbul University (19.169%), Ege University (10.863%), University of Health Sciences (9.265%), and Hacettepe University (8.626%). ACTHIV-IST (ACTion against HIV in Istanbul) study group (n = 3, 0.958) was Turkey's most productive HIV/AIDS research group. 87.220% of the studies were not funded. Conclusions: According to the findings, Turkey has limited HIV/AIDS research output. Furthermore, the majority of investigations were conducted by only a few centers. Because the study covered the entire country, and there are more centers that follow HIV/AIDS patients, these centers should also take part in the research. As a result, the current study emphasizes the importance of increasing targeted financing for HIV/AIDS research.Öğe Investigation of hematologic findings related to brucellosis in Anatolian region(Saudi Med J, 2024) Celik, Mehmet; Arslan, Yusuf; Topcu, Ertugrul; Sahinoglu, Mustafa Serhat; Altindag, Deniz; Gurbuz, Esra; Atalay, EbruObjectives: To investigate the prevalence of hematologic findings and the relationship between hemogram parameters and brucellosis stages in patients. Methods: This multi-center study included patients older than 16 years of age who were followed up with a diagnosis of brucellosis. Patients' results, including white blood cell, hemoglobin, neutrophil, lymphocyte, monocyte, mean platelet volume, platelet and eosinophil counts were analyzed at the initial diagnosis. Results: In this study 51.3% of the patients diagnosed with brucellosis were male. The age median was 45 years for female and 41 years for male. A total of 55.1% of the patients had acute brucellosis, 28.2% had subacute, 7.4% had chronic and 9% had relapse. The most common hematologic findings in brucellosis patients were anemia (25.9%), monocytosis (15.9%), eosinopenia (10.3%), and leukocytosis (7.1%). Pancytopenia occurred in 0.8% of patients and was more prominent in the acute phase. The acute brucellosis group had lower white blood cell, hemoglobin, neutrophil, eosinophil, and platelet counts and mean platelet volume, and higher monocyte counts compared to subacute and chronic subgroups. Conclusion: It was noteworthy that in addition to anemia and monocytosis, eosinopenia was third most prominent laboratory findings in the study. Pancytopenia and thrombocytopenia rates were low.
