Yazar "Rocha, Joao Miguel" seçeneğine göre listele

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    Functional chocolate: exploring advances in production and health benefits
    (Wiley, 2024) Saritas, Suemeyye; Duman, Hatice; Pekdemir, Burcu; Rocha, Joao Miguel; Oz, Fatih; Karav, Sercan
    Chocolate has been a part of human consumption for millennia, serving as a confection, medicine and aphrodisiac. Chocolate consumption is increasing worldwide, and independent of the age or social background. The substantial content of chocolate may provide consumers with antioxidant, anti-inflammatory, antimicrobial, antiallergenic, and anticarcinogenic benefits. Beyond such properties, diverse bioactive ingredients are utilised in the creation of functional chocolate products aiming at promoting health and meeting the modern consumers' demands and market orientations. These products are primarily focused on enhancing nutraceutical effects, such as antioxidant activity, protein content and prebiotic effects. Additionally, the use of A2 milk powder in chocolate production holds promising expectations towards enhancing the digestibility of the products. Due to the superior affinity of proteolytic enzymes, A2 milk can be digested more easily than A1 milk. In this way, with the addition of A2 milk to chocolate, it may become more easily digestible. The objectives of this review are a comprehensive understanding of the evolution of chocolate consumption, its health benefits, and the contemporary innovations in chocolate production. Additionally, the potential for developing easily digestible, functional chocolates made from A2 milk, which could rejuvenate functional chocolate production, is discussed in this article. The bioactive components contained in various types of chocolate have been shown in the graphical abstract. The bioactive components and amounts contained vary according to the type of chocolate. image
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    Role of bovine colostrum against various diseases
    (Elsevier, 2024) Yalcintas, Yalcin Mert; Duman, Hatice; Rocha, Joao Miguel; Bartkiene, Elena; Karav, Sercan; Ozogul, Fatih
    Colostrum refers to the initial milk that mammals generate following childbirth, and it possesses rich nutritional value. Due to its bioactive components (such as lactoferrin, lactoperoxidase, and immunoglobulins), colostrum actively contributes to various positive immune functions and specific cellular processes within the consumer's body. In clinical applications, research has shown that the immunoglobulins found in colostrum support the immune system, playing key roles in cell growth and development. Growth factors also contribute to various processes, including wound healing and metabolic functions. Lactoferrin and lactoperoxidase support the body's immunity, while another bioactive component, functional oligosaccharides, selectively promote growth in the microbiome. Additionally, nucleotide monophosphates play crucial roles in numerous vital physiological functions, including the synthesis of proteins, lipids, and carbohydrates. The supplementation of colostrum has shown promising results in combating various diseases caused by different pathogens, such as gastrointestinal infections, diarrhea, gut-barrier diseases, and inflammatory bowel disease. Based on reports of these clinical applications, the effects of colostrum against various diseases have been observed. Further research may reveal different therapeutic effects of colostrum on different diseases. By exploring the clinical applications of colostrum supplementation and the mechanisms of action of its bioactive components against specific diseases, this review highlights the potential of colostrum as a therapeutic agent and provides insights into its multifaceted effects.