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    Physical and chemical food safety hazards and associated health risks in seafood: A Mediterranean perspective (Part 1)
    (Academic Press Inc., 2024) Ozogul, Fatih; Rathod, Nikheel; Alak, Gonca; Colakoglu, Fatma; Ayas, Deniz; Baygar, Tacnur; Çaklı, Şükran
    Several risks to food safety are associated with seafood. The marine environment is heavily affected by various materials, both of physical and chemical nature, which have significant impact on the safety of seafood. Recently, there has been a concerning discovery regarding seafood contamination. As it appears, there are physical hazards present, specifically in the form of nano- and micro-plastic materials. Additionally, chemicals from various sources have been detected. These chemicals are commonly used in the production of convenience goods, antimicrobials, antibiotics, heavy metals and industrial effluents. This chapter has focused on the various hazards that can influence the safety of seafood in the marine environment. It covers both physical and chemical sources of these hazards, ensuring a comprehensive understanding of the potential risks involved. There are indications that the consumption of polluted seafood in the Mediterranean region can have negative impact on human health. © 2024
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    Role of bovine colostrum against various diseases
    (Elsevier, 2024) Yalcintas, Yalcin Mert; Duman, Hatice; Rocha, Joao Miguel; Bartkiene, Elena; Karav, Sercan; Ozogul, Fatih
    Colostrum refers to the initial milk that mammals generate following childbirth, and it possesses rich nutritional value. Due to its bioactive components (such as lactoferrin, lactoperoxidase, and immunoglobulins), colostrum actively contributes to various positive immune functions and specific cellular processes within the consumer's body. In clinical applications, research has shown that the immunoglobulins found in colostrum support the immune system, playing key roles in cell growth and development. Growth factors also contribute to various processes, including wound healing and metabolic functions. Lactoferrin and lactoperoxidase support the body's immunity, while another bioactive component, functional oligosaccharides, selectively promote growth in the microbiome. Additionally, nucleotide monophosphates play crucial roles in numerous vital physiological functions, including the synthesis of proteins, lipids, and carbohydrates. The supplementation of colostrum has shown promising results in combating various diseases caused by different pathogens, such as gastrointestinal infections, diarrhea, gut-barrier diseases, and inflammatory bowel disease. Based on reports of these clinical applications, the effects of colostrum against various diseases have been observed. Further research may reveal different therapeutic effects of colostrum on different diseases. By exploring the clinical applications of colostrum supplementation and the mechanisms of action of its bioactive components against specific diseases, this review highlights the potential of colostrum as a therapeutic agent and provides insights into its multifaceted effects.