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Öğe Accuracy and precision of cap thickness in small incision lenticule extraction(Dove Medical Press Ltd, 2013) Ozgurhan, Engin Bilge; Agca, Alper; Bozkurt, Ercument; Gencer, Baran; Celik, Ugur; Cankaya, Kadir IlKer; Demirok, AhmetAims: To report and compare the cap thickness predictability of small incision lenticule - extraction (SMILE) and flap thickness of femtosecond laser-assisted in situ keratomileusis (femto-LASIK). Settings and design: Beyoglu Eye Training and Research Hospital, Refractive Surgery Department, Istanbul, Turkey. Retrospective pilot study. Materials and methods: Medical records of patients who had SMILE in one eye and femtoLASIK in the other eye were reviewed. Visante corneal Optical Coherence Tomography (OCT) images at 1 week and 1month post-surgery were analyzed. Both cap and flap thickness at the temporal edge and the nasal edge were measured and compared to each other. Statistical analyses used: PAWS Statistics 18 and unpaired student t-test were used to compare the groups. Results: The study included 66 eyes of 33 patients (24.7 +/- 3.8 years, 20 females and 13 males). Mean flap thickness was 114.88 mu m +/- 4.96 mu m, and mean cap thickness was 114.63 mu m +/- 5.18 mu m. In group 1 (SMILE), cap thickness values were 115.84 mu m +/- 6.84 mu m, 114.75 mu m +/- 7.36 mu m, 113.66 mu m +/- 6.88 mu m, and 114.27 mu m +/- 6.90 mu m in measurement zones 1, 2, 3, and 4, respectively. In group 2 (FemtoLASIK), flap corneal thickness values were 115.96mmHg +/- 7.01mmHg, 114.72mmHg +/- 7.17mmHg, 113.54mmHg +/- 6.45mmHg, and 115.30mmHg +/- 6.64mmHg in measurement zones 1, 2, 3, and 4, respectively. In both groups, no statistically significant change within the measurement zones was observed. Conclusion: The predictability of cap thickness in SMILE surgery does not differ from the femto-LASIK flaps created using the same femtosecond laser platform.Öğe Comparison of conjunctival graft thickness after primary and recurrent pterygium surgery: Anterior segment optical coherence tomography study(Medknow Publications & Media Pvt Ltd, 2014) Ozgurhan, Engin Bilge; Kara, Necip; Bozkurt, Ercument; Gencer, Baran; Yuksel, Kemal; Demirok, AhmetObjective: The objective of the following study is to compare the conjunctival graft thickness measured with anterior segment optical coherence tomography (OCT) after primary and recurrent pterygium excision. Design: Prospective, interventional and comparative study. Participants: A total of 20 eyes of 20 patients with primary pterygium (primary group) and 20 eyes of 20 patients with recurrent pterygium (recurrent group) were enrolled. Materials and Methods: All patients underwent pterygium excision with conjunctival autograft transplantation. Conjunctival graft thickness was measured at 1 week, 1 month and 3 months after surgery using the Visante-OCT (Carl-Zeiss Meditec, Dublin, CA, USA). Main outcome measure was the mean conjunctival thickness determined as the mean of three measurements at 1, 2 and 3 mm posterior to the scleral spur. Results: There were no statistically significant differences in age, sex, or laterality between the groups. Mean thickness of the graft in primary and recurrent groups, respectively, was 430 +/- 127 mu m and 461 +/- 178 mu m at 1 week after surgery (P = 0.587), 114 +/- 19 mu m and 162 +/- 48 mu m at 1 month after surgery (P = 0.001) and 109 +/- 15 mu m and 107 +/- 18 mu m at 3 months after surgery (P = 0.726). Conclusion: The findings revealed that conjunctival thickness after primary or recurrent pterygium excision was greatest at 1 week after surgery and continued to decrease for up to 3 months. Mean graft thickness differed significantly between the two groups only at 1 month after surgery.Öğe Effect of Fluorometholone/Tetrahydrozoline Fixed Combination on Conjunctival Autograft Morphology after Primary Pterygium Excision(Hindawi Ltd, 2013) Ozgurhan, Engin Bilge; Kara, Necip; Bozkurt, Ercument; Gencer, Baran; Agca, Alper; Alkin, Zeynep; Demirok, AhmetPurpose. To evaluate the effect of a fluorometholone/tetrahydrozoline fixed combination on conjunctival graft morphology after primary pterygium excision. Methods. The patients who underwent pterygium excision with conjunctival autograft transplantation were randomized into three groups based on postoperative medications as the fluorometholone/tetrahydrozoline group, fluorometholone group, and dexamethasone group. Conjunctival graft thickness was measured with anterior segment optical coherence tomography. The conjunctival graft hyperemia was evaluated using a high definition external camera. Results. The mean graft thickness was significantly lower in the fluorometholone/tetrahydrozoline group compared with fluorometholone and dexamethasone groups at 2 weeks (P = 0.002 and P = 0.012, resp.) and at 1 month after surgery (P = 0.003 and P = 0.013, resp.). The conjunctival hyperemia score was significantly lower in the fluorometholone/tetrahydrozoline group compared with fluorometholone and dexamethasone groups at 2 weeks (P = 0.000 and P = 0.000, resp.) and at 1 month (P = 0.039 and P = 0.040, resp.). The graft thickness and conjunctival hyperemia score were similar among the groups at 1 week and 3 months (P > 0.05). Conclusion. The findings of the present study revealed that treatment with the fluorometholone/tetrahydrozoline fixed combination may be helpful to decrease graft edema and to achieve better cosmetic appearance at 2 weeks and 1 month after pterygium excision.Öğe Obesity and Obstructive Sleep Apnea in Patients With Keratoconus in a Turkish Population(Lippincott Williams & Wilkins, 2014) Gencer, Baran; Ozgurhan, Engin Bilge; Kara, Selcuk; Tufan, Hasan Ali; Arikan, Sedat; Bozkurt, Ercument; Demirok, AhmetPurpose:The aim of this study was to compare the frequency of occurrence of obesity and high risk of developing obstructive sleep apnea (OSA) in a keratoconus population with that of a control group.Methods:This prospective, case-controlled multicenter study was performed on patients with keratoconus and age- and gender-matched control subjects. One hundred forty-six patients were included in each group, and the Berlin Questionnaire was used for classifying patients as having a high risk or low risk of developing OSA. The patients' demographic and clinical characteristics were compared with the Mann-Whitney U test for continuous variables and with the (2) test for categorical variables.Results:The keratoconus (85 male/61 female) and control (79 male/67 female) groups' median ages were 25 (8-65) and 24 (9-60) years, respectively. Of the 146 patients in each group, 11 (7.5%) patients were determined to be at a high risk of developing OSA in the keratoconus group, and 8 (5.5%) patients were determined to be at a high risk of developing OSA in the control group. There was no significant difference between the groups (P = 0.477). The keratoconus and control groups' median body mass index values were found to be within normal ranges of 23.2 and 23.4, respectively.Conclusions:In this study, the mean body mass index value of the keratoconus group was determined to be within normal limits. In a Turkish population, the ratio of a high risk of developing OSA was not found to be significantly different between the keratoconus and control groups.